(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on

Bezeichnung:(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on

CAS-Nr13241-33-3

Englisch Name:Neohesperidin

CBNumberCB6291569

SummenformelC28H34O15

Molgewicht610.56

MOL-Datei13241-33-3.mol

Synonyma

(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on

(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	239-243°C
Siedepunkt	933.7±65.0 °C(Predicted)
Dichte	1.65±0.1 g/cm3(Predicted)
Dampfdruck	0Pa at 20℃
storage temp.	Sealed in dry,2-8°C
Löslichkeit	DMSO (Slightly), Pyridine (Slightly)
pka	7.14±0.40(Predicted)
Aggregatzustand	Solid
Farbe	White to Off-White
Wasserlöslichkeit	3.98mg/L at 20℃
BRN	74945
InChIKey	ARGKVCXINMKCAZ-RTFRIYMLSA-N
LogP	-0.69 at 20℃
CAS Datenbank	13241-33-3(CAS DataBase Reference)

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
RTECS-Nr.	DJ2981400
F	10-21
HS Code	29389090

Gefahreninformationscode (GHS)

Neohesperidin Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.
Chemische Eigenschaften
White powder, easily soluble in methanol and almost insoluble in ether, derived from trifoliate orange peel, sour orange immature fruit, and various citrus fruits.
Verwenden
Neohesperidin can be used in cosmetic products and as a sweetening agent in food & beverages, an antioxidant flavanone glycoside
Verwenden
Neohesperidin exhibits lipid-regulating effects in vivo and in vitro. It is a main flavonoid in citrus byproducts (CBP) which possesses anti-oxidant activity.
Definition
ChEBI: Neohesperidin is a flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. It has a role as an antineoplastic agent and a plant metabolite. It is a neohesperidoside, a disaccharide derivative, a dihydroxyflavanone, a member of 3'-hydroxyflavanones, a monomethoxyflavanone, a flavanone glycoside and a member of 4'-methoxyflavanones. It is functionally related to a hesperetin.

Neohesperidin Upstream-Materialien And Downstream Produkte

(S)-7-[[2-O-6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

13241-33-3, Neohesperidin Verwandte Suche:

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