Pyridazin-3,6-diol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

  H341：Kann vermutlich genetische Defekte verursachen.

• Sicherheit

  P201：Vor Gebrauch besondere Anweisungen einholen.

  P202：Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.

  P261：Einatmen von Staub vermeiden.

  P302+P352：BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P308+P313：BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.

Maleic hydrazide Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  R40:Verdacht auf krebserzeugende Wirkung.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
  S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
  S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

• Beschreibung

  Maleic Hydrazide is a crystalline solid. Molecular weight= 112.10; Freezing/Melting point=292℃ (decomposes at 260℃); also reported as .300℃. Hazard Identification (based on NFPA-704 M Rating System): Health 2, Flammability 1, Reactivity 0. Slightly soluble in cold water; more soluble in hot.

• Chemische Eigenschaften

  Maleic hydrazide is a colorless crystalline solid. Odorless.

• Chemische Eigenschaften

  Maleic hydrazide is a crystalline solid

• Verwenden

  Growth regulator used to control the sprouting of potatoes and onions and to prevent sucker development on tobacco, fruits, ornamentals, vines, field crops and in forestry. Also used to control insects in warehouses, storerooms, empty sacks and in animal and poultry houses.

• Verwenden

  Maleic Hydrazide is used in plant growth regulator formulations.

• Verwenden

  Experimentally in horticulture and agriculture. To control suckering of tobacco. In the synthesis of pyridazine.

• Definition

  ChEBI: Maleic hydrazide is a pyridazinone.

• Vorbereitung Methode

  Maleic hydrazide is slightly acidic. It is made by treating maleic anhydride with hydrazine hydrate in alcohol.

• Synthesis Reference(s)

  Journal of the American Chemical Society, 73, p. 1873, 1951 DOI: 10.1021/ja01148a537

• Allgemeine Beschreibung

  Odorless white solid. Sinks in water.

• Air & Water Reaktionen

  Insoluble in water.

• Reaktivität anzeigen

  3,6-Dihydroxypyridazine can be decomposed by oxidizing agents. 3,6-Dihydroxypyridazine can also be decomposed by strong acids. 3,6-Dihydroxypyridazine forms water-soluble alkali-metal and amine salts. 3,6-Dihydroxypyridazine is slightly acidic and may be titrated as a monobasic acid. Mild oxidation produces a compound which reacts instantly with dienes at -107° F to form crystalline derivatives. 3,6-Dihydroxypyridazine is slightly corrosive to iron and zinc. 3,6-Dihydroxypyridazine is incompatible with pesticides that are highly alkaline in reaction. In the presence of heavy metal and iron, zinc, calcium and magnesium ions, sparingly-soluble salts are formed.

• Hazard

  Toxic by ingestion. Questionable carcinogen.

• Health Hazard

  Inhalation of dust causes irritation of nose and throat. Contact with eyes or skin causes irritation. Ingestion has been observed to cause tremors and muscle spasms in test animals.

• Brandgefahr

  Special Hazards of Combustion Products: Toxic nitrogen oxides are produced.

• Landwirtschaftliche Anwendung

  Herbicide, Plant growth regulator, Fungicide: Banned for use in EU countries. Actively registered for use in the U.S. Maleic hydrazide is a plant growth regulator (sprout inhibitor) and herbicide that is registered for use on tobacco, potatoes, onions, non-bearing citrus, turf, utility and highway rights-of-way, airports, industrial land, lawns, recreational areas, ornamental/shade trees and ornamental plants. Most of the use of maleic hydrazide in the U.S. is on tobacco.

• Handelsname

  BH DOCK KILLER®; BOS MH®; BURTOLIN®; CHEMFORM®; DE-CUT®; DESPROUT D REXEL-SUPER P®; EC 300®; FAIR 30®; FAIR PLUS®; FAIR PS®; MAINTAIN 3®; MALEIN 30®; MALAZIDE®; MH 30®; MH 40®; MH 36 BAYER®; PO-SAN® (with 9H-Fluorene-9-carboxylic acid, 2-chloro-9-hydroxy-, methyl ester)®; REGULOX®; REGULOX W®; REGULOX 50 W®; RETARD®; ROYAL MH 30®; ROYAL SLO-GRO®; SLO-GRO®; SPROUT-STOP®; STUNTMAN®; SUCKER-STUFF®; SUPER DE-SPROUT®; SUPER SPROUT STOP®; VONDALDHYDE®; VONDRAX®

• Sicherheitsprofil

  Moderately toxic by ingestion. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Can cause chronic liver damage and acute central nervous system effects. When heated to decomposition it emits hghly toxic fumes of NOx See also HYDRAZINE.

• mögliche Exposition

  Maleic hydrazide is a pyridazine/ pyridazinone herbicide, plant growth regulator, and fungicide that is registered for use on tobacco, potatoes, onions, nonbearing citrus, turf, utility and highway rights-of-way, airports, industrial land, lawns, recreational areas, ornamental/ shade trees and ornamental plants. Most of the use of maleic hydrazide in the United States is on tobacco. Banned for use in EU countries. Actively registered for use in the United States

• Erste Hilfe

  Skin Contact: Flood all areas of body that have contacted the substance with water. Do not wait to remove contaminated clothing; do it under the water stream. Use soap to help assure removal. Isolate contaminated clothing when removed to prevent contact by others. Eye Contact: Remove any contact lenses at once. Flush eyes well with copious quantities of water or normal saline for at least 2023 min. Seek medical attention. Inhalation: Leave contaminated area immediately; breathe fresh air. Proper respiratory protection must be supplied to any rescuers. If coughing, difficult breathing, or any other symptoms develop, seek medical attention at once, even if symptoms develop many hours after exposure. Ingestion: If convulsions are not present, give a glass or two of water or milk to dilute the substance. Assure that the person’s airway is unobstructed and contact a hospital or poison center immediately for advice on whether or not to induce vomiting.

• Carcinogenicity

  Mice fed up to 3 mg/kg for 320 ‘days showed no carcinogenic effect when sacrificed at 2 years of age. Mice fed 0, 1000, 3200, and 10,000 ppm in the diet in 23 months showed no oncogenic effect. Rats were fed diets providing doses of 0, 25, 500, or 1000 mg/kg. Occasional increases in tumor incidences were seen, but as these were not consistent between the two sexes and did not achieve statistical significance, they are considered not attributable to maleic hydrazide.
  Application of maleic hydrazide to the skin three times a week up to a cumulative dose of 300mg was not carcinogenic . Oral treatment of dogs and rats for 17–28 months resulted in no excess cancer in any tissue or organs. Subcutaneous injections of maleic hydrazide in newborn mice produced a very slight increase in liver tumors, although this finding is generally considered negative. A study in which maleic hydrazide was given subcutaneously to mice (55 mg total over 49 weeks) showed no evidence of a carcinogenic response was seen.

• Environmental Fate

  Soil. The half-life in soil was reported to be 2–8 weeks (Hartley and Kidd, 1987). When maleic hydrazide was applied to muck, sand and clay at concentrations of 0.7 and 2.7, 1.0 and 3.75 and 0.85 and 3.4 ppm, 86 and 100, 87 and 100 and 47 and 67% degradation yields were obtained, respectively (Hoffman et al., 1962).
  Plant. Major plant metabolites include fumaric, succinic and maleic acids (Hartley and Kidd, 1987).
  Photolytic. In water, maleic hydrazide showed an absorption maximum at 300 nm indicating direct photolysis should occur (Gore et al., 1971).
  Chemical/Physical. Reacts with alkalies and amines forming water-soluble salts (Hartley and Kidd, 1987). Decomposed by oxidizing acids releasing nitrogen (Worthing and Hance, 1991). Decomposes at 260°C (Windholz et al., 1983) releasing toxic fumes of nitrogen oxides (Sax and Lewis, 1987).

• Lager

  Color Code—Green: General storage may be used. Prior to working with this chemical you should be trained on its proper handling and storage. Store in a refrigerator or a cool, dry place.

• Versand/Shipping

  UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

• läuterung methode

  Crystallise the hydrazide from water. Dry it at ~100o over P2O5. [Beilstein 24 III/IV 1186.]

• Inkompatibilitäten

  Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Slightly corrosive to iron and zinc. Maleic hydrazide forms water-soluble alkali-metal and amine salts. It is slightly acidic and may be titrated as a monobasic acid. Mild oxidation produces a compound which reacts instantly with dienes at 277C/ 2 107F to form crystalline derivatives. It is incompatible with pesticides that are highly alkaline in reaction. This chemical is slightly corrosive to iron and zinc. In the presence of heavy metal and iron, zinc, calcium, and magnesium ions, sparingly soluble salts are formed.

• Waste disposal

  Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

Maleic hydrazide Upstream-Materialien And Downstream Produkte

Pyridazin-3,6-diol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(474)Suppliers

123-33-1, Maleic hydrazide Verwandte Suche: