α-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine

α-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Amphecloral,ZYF Pharm Chemical

• Verwenden

  Anorexic.

• Definition

  ChEBI: Amfecloral is a member of amphetamines.

• Manufacturing Process

  Molar equivalents of d-amphetamine base and chloral hydrate were dissolved in benzene and the solution was heated to distill off benzene and water, azeotropically. Two molar equivalents of water were separated in this manner. The remainder of the benzene was distilled off, leaving a liquid residue which was then fractionally distilled to yield the clear, colorless liquid condensation product, N-[2-(1-phenylpropyl)]-2,2,2-trichloroethylidenimine, which boiled at 95°C/0.5 mm and had an index of refraction, nD 20 of 1.530 and a specific optical rotation of +49.9(+/-)0.3° [in dioxane].
  Following the above procedure but using dl-amphetamine, the DL-form of N- [2-(1-phenyl-propyl)]-2,2,2-trichloroethylidemmine was also prepared. It had the same boiling point and index of refraction as the (-)-form above but its specific optical rotation was zero.

• Therapeutic Function

  Anorexic

α-Methyl-N-(2,2,2-trichloroethylidene)benzeneethanamine Upstream-Materialien And Downstream Produkte