DIHYDROERGOTAMINE MESYLATE

DIHYDROERGOTAMINE MESYLATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.

• S-Sätze Betriebsanweisung:

  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

• Originator

  Redergin,Lek

• Verwenden

  Cognition adjuvant.

• Manufacturing Process

  Dihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur. (Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine, ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was filtered off, a filtrate was distilled to dryness in vacuum. The residue was in chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered off, the filtrate was crystallized after adding of hot benzene and cooling. Yield 6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C.

• Trademarks

  Alkergot (Sandoz); Circanol(3M Pharmaceuticals); Deapril (Bristol-Myers Squibb);Gerimal (Watson); Hydergine (Novartis).

• Therapeutic Function

  Vasodilator

DIHYDROERGOTAMINE MESYLATE Upstream-Materialien And Downstream Produkte

11032-41-0, DIHYDROERGOTAMINE MESYLATE Verwandte Suche: