Anti-DAPK1, Anti-DAPK, Anti-Death associated protein kinase 1

Anti-DAPK1, Anti-DAPK, Anti-Death associated protein kinase 1 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-DAP Kinase 1 antibody is suitable for use in immunoprecipitation (2.5-5.0 μg using extracts of human HeLa cells) and western blot (1-2 μg/mL using whole extracts of human HeLa cells).

• Allgemeine Beschreibung

  DAP-kinase 1 is a Ca²⁺/calmodulin dependent Ser/Thr kinase that associates with microfilaments. The protein is composed of a multidomain structure. It has a subdomain typical of serine/threonine kinases, a Ca²⁺/calmodulin regulatory domain, eight ankyrin repeats followed by two P-loop motifs and a typical death domain module. It contains two auto-inhibitory domains, one being Ca²⁺/calmodulin dependent.

• Biochem/physiol Actions

  Death-associated protein kinase (DAPK) belongs to the serine/threonine kinase family that regulates apoptosis, growth factor signaling and also may be involved in modulating immune responses. DAPK1 mediates cellular functions such as membrane blebbing and autophagy and inhibits the activity of prolyl isomerase

Anti-DAPK1, Anti-DAPK, Anti-Death associated protein kinase 1 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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