Sulfathiazolnatrium

Bezeichnung:Sulfathiazolnatrium

CAS-Nr144-74-1

Englisch Name:Sulfathiazole sodium

CBNumberCB6170572

SummenformelC9H10N3NaO2S2

Molgewicht279.31

MOL-Datei144-74-1.mol

Synonyma

Sulfathiazolnatrium

Sulfathiazolnatrium physikalisch-chemischer Eigenschaften

storage temp.	Store at -20°C
Löslichkeit	H2O: soluble50mg/mL
Aggregatzustand	powder
Farbe	white to off-white
BRN	3802297
Stabilität	Hygroscopic
InChI	InChI=1S/C9H9N3O2S2.Na.H/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;;/h1-6H,10H2,(H,11,12);;
InChIKey	PLYRQFRFHFKJLU-UHFFFAOYSA-N
SMILES	S(C1C=CC(N)=CC=1)(=O)(=O)NC1SC=CN=1.[NaH]
CAS Datenbank	144-74-1(CAS DataBase Reference)
EPA chemische Informationen	Benzenesulfonamide, 4-amino-N-2-thiazolyl-, monosodium salt (144-74-1)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-24/25-23
WGK Germany	2
RTECS-Nr.	WP2450000
F	10

Gefahreninformationscode (GHS)

Sulfathiazole sodium Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
Beschreibung
Sulfathiazole sodium salt is a short-acting sulfa drug. It was a common oral and topical antibiotic until less toxic alternatives were discovered. It is no longer used in humans. Sulfathiazole is added to the diet of laboratory animals to inhibit folate formation by gut bacteria. This ensures that the animal′s only source of available folate is from their diet. Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
Verwenden
Sulfathiazole sodium salt is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA). It can also be used in biological study of thermotherapy and sulfonamide antibiotics deciphered Cyanobacteria and Proteobacteria microbiome in huanglongbing-affected Citrus paradise and Citrus limon.
Allgemeine Beschreibung
Chemical structure: sulfonamide
Biochem/physiol Actions
Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Sulfathiazolnatrium Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

144-74-1, Sulfathiazole sodium Verwandte Suche:

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