ANTI-NEOMYCIN PHOSPHOTRANSFERASE II

ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Anti-NPTII antibody has been used in immunoblotting.

• Allgemeine Beschreibung

  Neomycin phosphotransferase II (NPTII) gene also known as the kanamycin-resistance marker gene, encoding for NPTII (30 kDa) an aminoglycoside 3′ -phosphotransferase II (APHII), was isolated from the E. coli transposon Tn5.

• Biochem/physiol Actions

  The Neomycin phosphotransferase II (NPTII) gene confers resistance to some aminoglycoside antibiotics including neomycin and kanamycin in bacteria and plant cells and to G418 (Gibco Geneticin reagent) sulfate in mammalian cells. NPTII phosphorylates and inactivates kanamycin, preventing kanamycin from binding to the 30S ribosomal subunit to inhibit protein synthesis, thus rendering cells resistant to the antibiotic. NPTII serves as a marker for the selection of genetically engineered crops.

ANTI-NEOMYCIN PHOSPHOTRANSFERASE II Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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