cannabichromene

Bezeichnung:cannabichromene

CAS-Nr20675-51-8

Englisch Name:cannabichromene

CBNumberCB61400957

SummenformelC21H30O2

Molgewicht314.46

MOL-Datei20675-51-8.mol

cannabichromene physikalisch-chemischer Eigenschaften

Schmelzpunkt	145°C
Siedepunkt	394.13°C (rough estimate)
Dichte	1.0536 (rough estimate)
Brechungsindex	1.5404 (estimate)
Flammpunkt	9℃
storage temp.	-20°C
Löslichkeit	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Aggregatzustand	Oil
pka	9.68±0.40(Predicted)
Farbe	Crystals
InChI	InChI=1S/C21H30O2/c1-5-6-7-10-17-14-19(22)18-11-13-21(4,23-20(18)15-17)12-8-9-16(2)3/h9,11,13-15,22H,5-8,10,12H2,1-4H3
InChIKey	UVOLYTDXHDXWJU-UHFFFAOYSA-N
SMILES	C1(C)(CC/C=C(\C)/C)OC2=CC(CCCCC)=CC(O)=C2C=C1
LogP	8.560 (est)

Sicherheit

RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	1
HS Code	9999999999
Toxizität	dni-hmn:lyms 100 mmol/L FEPRA7 36,1748,77

Gefahreninformationscode (GHS)

cannabichromene Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Cannabichromene (CBC) is one of the most abundant cannabinoids found in the cannabis plant, next to CBD, THC, and CBG. It is particularly abundant in freshly harvested dry-type Cannabis material, and it is the second most abundant cannabinoid in some strains of marijuana growing in the USA. Like CBD, CBG does a poor job of binding to the endocannabinoid system's CB1 and CB2 receptors and is a non-psychoactive compound. Instead, CBC has been observed to have unique interactions with TRPV1 and TRPA1 receptors (vanilloid 1 and ankyrin 1 receptors). It has modest antinociceptive and anti‐inflammatory effects and potentiates some effects of Δ9‐tetrahydrocannabinol in vivo[1–2].
Definition
ChEBI: Cannabichromene is a 1-benzopyran.
Allgemeine Beschreibung
Cannabichromene (CBC) is a non-psychoactive cannabinoid of Cannabis that reportedly exerts anti-inflammatory, antimicrobial and analgesic activity. This Certified Snap-N-Spike^? solution standard is suitable for cannabichromene testing methods by GC/MS, HPLC or LC-MS/MS for Cannabis potency testing or impurity profiling, pharmaceutical research, and forensic analysis. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.
Biologische Aktivität
Cannabichromene (CBC) is a selective CB2 receptor agonist displaying higher efficacy than tetrahydrocannabinol in hyperpolarizing AtT20 cells. CBC can also recruit CB2 receptor regulatory mechanisms. CBC may contribute to the potential therapeutic effectiveness of some cannabis preparations, potentially through CB2 receptor‐mediated modulation of inflammation[2].
Sicherheitsprofil
Poison by intravenous and intraperitoneal routes. Experimental reproductive effects. Mutation data reported. Whenheated to decomposition it emits acrid smoke and irritating fumes
target
NOS | COX | ERK | ATPase
Einzelnachweise
[1] Angelo A Izzo. “Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice.” British Journal of Pharmacology 166 4 (2012): 1444–1460.
[2] Michael Udoh. “Cannabichromene is a cannabinoid CB2 receptor agonist.” British Journal of Pharmacology 176 23 (2019): 4537–4547.

cannabichromene Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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