bermoprofen

bermoprofen Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Bermoprofen,ZYF Pharm Chemical

• Definition

  ChEBI: Bermoprofen is a dibenzooxazepine.

• Manufacturing Process

  A mixture of dl-2-[4-(2'-carboxymethyl-4'-methylphenoxy)phenyl]propionic acid (15.3 g) and polyphosphoric acid (92 g) was heated with stirring at 110- 120°C for 2 hours. To the reaction mixture was added water and the resulting mixture was extracted with chloroform. The organic layer was washed with water, dried over anhydrous sodium sulfate and concentrated. The residue was chromatographed on silica gel (75 g) using chloroform as an eluent to give a crude product, which was recrystallized from toluene to give the dl-2-(8- methyl-10,11-dihydro-11-oxodibenz[b,f]oxepin-2-yl)propionic acid (9.4 g, 65.3%), m.p. 128-129°C.

• Therapeutic Function

  Antiinflammatory, Antipyretic

bermoprofen Upstream-Materialien And Downstream Produkte

bermoprofen Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(5)Suppliers