PHALLACIDIN Struktur

PHALLACIDIN

Bezeichnung:PHALLACIDIN

CAS-Nr26645-35-2

Englisch Name:PHALLACIDIN

CBNumberCB6136097

SummenformelC37H50N8O13S

Molgewicht846.9

MOL-Datei26645-35-2.mol

PHALLACIDIN physikalisch-chemischer Eigenschaften

Dichte	1.1678 (rough estimate)
Brechungsindex	1.7400 (estimate)
Löslichkeit	DMF: Soluble; DMSO: Soluble; Methanol: Soluble; Water: Soluble
Aggregatzustand	White to off-white powder.
Farbe	White to off-white

Sicherheit

Kennzeichnung gefährlicher	T+
R-Sätze:	26/27/28
S-Sätze:	22-36/37/39-45
RIDADR	1544
WGK Germany	3
RTECS-Nr.	GT8943000
HazardClass	6.1(a)
PackingGroup	I
HS Code	2934999090

Gefahreninformationscode (GHS)

PHALLACIDIN Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Beschreibung
Phallacidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds filamentous actin (F-actin) like phalloidin , but contains a carboxyl group for coupling reactions.
Verwenden
Toxin Phallacidin is a weak fluorescent bicyclic peptide probe in aquous solution, Which is isolated from Amanita phalloides mushroom and could be used for blocking F-actin staining by labeled phallotoxins, which promotes actin polymerization.
Verwenden
Phallacidin is a natural mycotoxin first isolated from the death cap mushroom. It binds filamentous actin like phalloidin.
Definition
ChEBI: A homodetic bicyclic heptapeptide having a sulfide bridge.
Biochem/physiol Actions
Phallacidin, which is a bicyclic toxin from the Amanita phalloides mushroom, has been shown to inhibit F-actin degradation by proteolytic enzymes including trypsin and α-chymotrypsin.
Enzyminhibitor
This cyclic heptapeptide toxin (FWfree-acid = 846.92 g/mol; CAS 26645-35-2) from the poisonous green fungus Amanita phalloides stabilizes actin filaments and inhibits actin filament depolymerization. NBD phallacidin is a high-affinity, filamentous actin probe consisting of rabbit actin that is conjugated by reacting its thiol group with 4-chloro-7- nitrobenzofurazan, a yellow-green fluorescent dye. NBD phallacidin (Excitation at 465 nm; Emission at 536 nm) selectively stains F-actin un a manner that is superior to antibody staining, preferably in fixed and permeabilized samples. See Phalloidin

PHALLACIDIN Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

26645-35-2, PHALLACIDIN Verwandte Suche:

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