3'-fluoro-3'-deoxyadenosine

3'-fluoro-3'-deoxyadenosine Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  3'-deoxy-3'-fluoroadenosine can be used as pharmaceutical intermediates for pharmaceutical experimental research.

• Biologische Aktivität

  3'-Fluoro-3'-deoxyadenosine was active against a broad range of viruses, encompassing both DNA viruses [pox (vaccinia)], single-stranded (+) RNA viruses [picorna (polio, Coxsackie B), toga (sindbis, Semliki Forest)] and double-stranded RNA viruses (reo). Its antiviral activity spectrum, 3'-fluoro-3'-deoxyadenosine, clearly differed from those adenosine analogs known as inhibitors of S-adenosylhomocysteine hydrolase. 3'-Fluoro-3'-deoxyadenosine also proved effective in vivo in inhibiting tail lesion formation in mice inoculated intravenously with vaccinia virus[1].

• Einzelnachweise

  [1] A. Van Aerschot. “Synthesis and antiviral activity evaluation of 3′-fluoro-3′-deoxyribonucleosides: broad-spectrum antiviral activity of 3′-fluoro-3′-deoxyadenosine.” Antiviral research 12 3 (1989): Pages 133-150.

3'-fluoro-3'-deoxyadenosine Upstream-Materialien And Downstream Produkte

3'-fluoro-3'-deoxyadenosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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