PG 501

PG 501 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Pentona, Tanabe ,Japan ,1978

• Definition

  ChEBI: Mazaticol hydrochloride is an organic molecular entity.

• Manufacturing Process

  A mixture of 1.0 g of 6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol, methyl α,α-di-(2-thienyl)-glycolate and 30 mg of metallic sodium is heated at 80°C to 90°C for about 2 hours under reduced pressure. After cooling, ether is added to the reaction mixture. The mixture is extracted with 10% hydrochloric acid. The aqueous layer is alkalified with sodium carbonate and reextracted with ethyl acetate. The extract is washed with water, dried and concentrated to dryness. The residue thus obtained is treated with hydrogen chloride by conventional manner. 2.0 g of the α,α-di-(2-thienyl)glycolate of 6,6,9- trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol hydrochloride are obtained. Yield 83%.

• Therapeutic Function

  Antiparkinsonian

PG 501 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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