Phenylhydroxylamin

Bezeichnung:Phenylhydroxylamin

CAS-Nr100-65-2

Englisch Name:N-Phenylhydroxylamine

CBNumberCB5851746

SummenformelC6H7NO

Molgewicht109.13

MOL-Datei100-65-2.mol

Synonyma

Phenylhydroxylamin

Phenylhydroxylamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	80-84℃
Siedepunkt	204.59°C (rough estimate)
Dichte	1.1143 (rough estimate)
Brechungsindex	1.5444 (estimate)
storage temp.	-20°C
pka	9.00±0.70(Predicted)
Aggregatzustand	solid
Farbe	Light brown
Wasserlöslichkeit	20g/L(5 ºC)
Stabilität	Unstable - deteriorates with storage. Incompatible with strong oxidizing agents.
InChI	1S/C6H7NO/c8-7-6-4-2-1-3-5-6/h1-5,7-8H
InChIKey	CKRZKMFTZCFYGB-UHFFFAOYSA-N
SMILES	ONc1ccccc1
EPA chemische Informationen	Phenylhydroxylamine (100-65-2)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	25
S-Sätze:	45
RIDADR	UN 2811
WGK Germany	3
RTECS-Nr.	NC4900000
TSCA	TSCA listed
HazardClass	6.1
PackingGroup	Ⅲ
HS Code	2928009090
Speicherklasse	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral
Giftige Stoffe Daten	100-65-2(Hazardous Substances Data)

Gefahreninformationscode (GHS)

N-Phenylhydroxylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
tan powder or crystals
Verwenden
N-Phenylhydroxylamine can be used as a starting material for the synthesis of:
- 2-alkylindoles by treating with aliphatic terminal alkynes using gold catalyst via sequential 3,3-rearrangements and cyclodehydrations.
- Isoxazolidines by reacting with aldehydes and α, β-unsaturated aldehydes via a three-component one-pot catalytic reaction.
- Tetrahydro-1,2-oxazines by treating with an aldehyde and cyclopropane via homo 3+2 dipolar cycloaddition reaction.
Verwenden
Manufacture of cupferron.
Definition
ChEBI: N-phenylhydroxylamine is an N-substituted amine that is a derivative of aniline in which one of the amino hydrogen atoms is replaced with a hydroxy substituent.
synthetische
To a dispersion of 180 gm (2.75 gm-atom) of zinc dust in 500 ml of 50% aqueous ethanol, with vigorous stirring, is added 130 ml (156 gm, 1.27 mole) of nitrobenzene. The reaction is initiated by the dropwise addition of an aqueous ammonium chloride solution and can thereafter be maintained at a controllable rate by the cautious addition of the remaining ammonium chloride solution. The reaction temperature rises during this reduction step. Once reflux has subsided, the basic zinc salts are filtered off using a sintered glass funnel. The light green filtrate is cooled in an ice-salt mixture to precipitate the product. The yield is 100 gm (72.2%), m.p. 81°C.
The reduction of 2-methyl-2-nitropropane is carried out in a similar manner at 10-20°C to afford a 68% yield of N-t-butylhydroxylamine (m.p. 60-62°C).
Allgemeine Beschreibung
Tan to brown crystals.
Air & Water Reaktionen
Soluble in hot water.
Reaktivität anzeigen
N-Phenylhydroxylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Brandgefahr
Flash point data for N-Phenylhydroxylamine are not available but N-Phenylhydroxylamine is probably nonflammable.
Sicherheitsprofil
Poison by ingestion and subcutaneous routes. Human systemic effects by skin contact: primary irritation. Preparative hazard. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
läuterung methode
Impure base deteriorates rapidly. Crystallise it from H2O, *C6H6 or *C6H6/pet ether (40-60o). The picrate has m 186o (from EtOH), and the benzenesulfonate salt has m 70o (dec )(EtOH/*C6H6). [Beilstein 15 H 2, 15 I 3, 15, II 4, 15 III 5. 15 IV 4.]

N-Phenylhydroxylamine Upstream-Materialien And Downstream Produkte

Phenylhydroxylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

100-65-2, N-Phenylhydroxylamine Verwandte Suche:

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