SNAP

SNAP Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

• Chemische Eigenschaften

  Green Crystalline Solid

• Verwenden

  The D-isomer of SNAP. Serves as an NO donor.

• Definition

  ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.

• Allgemeine Beschreibung

  Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t_1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.

• Biologische Aktivität

  A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.

• Biochem/physiol Actions

  EC50 = 130 nM in relaxation of isolated bovine coronary artery rings

• Lager

  Store at -20°C

SNAP Upstream-Materialien And Downstream Produkte

SNAP Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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