TK05

TK05 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM[1]. TK05 reduces LTC4 production in a dose-dependent manner with an IC50 value of 318 ± 60 nM in MM6 Cells[1]. TK05 (0.12-6 mg/kg; given i.p.; only once) significantly reduces LTE4 levels[1].

• Einzelnachweise

  [1]. Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase. J Pharmacol Exp Ther. 2015 Oct;355(1):108-16.

TK05 Upstream-Materialien And Downstream Produkte

TK05 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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