Bromamphenicol

Bromamphenicol Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol.¹ It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.²

• Einzelnachweise

  1. Manyan, D.R., Arimura, G.K., and Yunis, A.A. Comparative metabolic effects of chloramphenicol analogues Mol. Pharmacol. 11(5),520-527(1975).
  2. Pettigrew, D.M., Roversi, P., Davies, S.G., et al. A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol Acta Crystallogr. D Biol. Crystallogr. 65(Pt 6),513-522(2009).

Bromamphenicol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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