Guanadrel HeMisulfate

Guanadrel HeMisulfate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Guanadrel is an orally active postganglionic sympathetic inhibitor. Guanadrel is used as an antihypertensive.

• Verwenden

  Guanadrel is an orally active postganglionic sympathetic inhibitor. Guanadrel HeMisulfate is used as an antihypertensive.

• Definition

  ChEBI: A sulfate salt resulting from the reaction of 2 eq. guanadrel with 1 eq. sulfuric acid. A postganglionic adrenergic blocking agent formerly used for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthosta ic hypotension (dizzy spells on standing up or stretching).

• Trademarks

  Hylorel (Pharmacia & Upjohn).

• Allgemeine Beschreibung

  Guanadrel sulfate, (1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanadine sulfate (Hylorel), issimilar to guanethidine monosulfate in the manner in whichit reduces elevated blood pressure. It acts as a postganglionicadrenergic blocking agent by displacing norepinephrinein adrenergic neuron storage granules, therebypreventing release of the endogenous neurotransmitter onnerve stimulation. Guanadrel sulfate has a much shorterhalf-life (10 hours) than guanethidine monosulfate, whose half-life is measured in days. In the stepped-care approachto hypertension, guanadrel sulfate is usually a step 2 agent.

Guanadrel HeMisulfate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(12)Suppliers

22195-34-2, Guanadrel HeMisulfate Verwandte Suche: