HC≡C-CH2-PEG3-SH

HC≡C-CH2-PEG3-SH Chemische Eigenschaften,Einsatz,Produktion Methoden

• Biologische Aktivität

  Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

• Einzelnachweise

  [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HC≡C-CH2-PEG3-SH Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(9)Suppliers

1412905-18-0, HC≡C-CH2-PEG3-SH Verwandte Suche: