4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenon

Bezeichnung:4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenon

CAS-Nr81-14-1

Englisch Name:Musk ketone

CBNumberCB5458527

SummenformelC14H18N2O5

Molgewicht294.3

MOL-Datei81-14-1.mol

Synonyma

4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenon

4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenon physikalisch-chemischer Eigenschaften

Schmelzpunkt	134-137 °C
Siedepunkt	436.08°C (rough estimate)
Dichte	1.2051 (rough estimate)
Dampfdruck	0.001Pa at 25℃
Brechungsindex	1.5110 (estimate)
Flammpunkt	2 °C
storage temp.	2-8°C
Löslichkeit	DMSO : 250 mg/mL (849.47 mM; Need ultrasonic)
Aggregatzustand	Solid
Farbe	White to off-white
Geruch (Odor)	at 10.00 % in benzyl benzoate. fatty musk soapy dry floral powdery
Geruchsart	musk
Wasserlöslichkeit	Insoluble (<0.1 g/100 mL at 20 ºC)
BRN	2062638
Stabilität	Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
InChIKey	WXCMHFPAUCOJIG-UHFFFAOYSA-N
LogP	4.24 at 25℃
CAS Datenbank	81-14-1(CAS DataBase Reference)
NIST chemische Informationen	2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone(81-14-1)
EPA chemische Informationen	Musk ketone (81-14-1)

Sicherheit

Kennzeichnung gefährlicher	F,Xn,N
R-Sätze:	11-20/21/22-36-50/53-40
S-Sätze:	16-36/37-61-60-46
RIDADR	UN1648 3/PG 2
WGK Germany	2
RTECS-Nr.	KM5775841
HS Code	2914790060
Giftige Stoffe Daten	81-14-1(Hazardous Substances Data)
Toxizität	Both the acute oral LD₅₀ in rats and the acute dermal LD₅₀ in rabbits exceeded 10 g/kg (Fogleman, 1970).

Gefahreninformationscode (GHS)

Musk ketone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R11:Leichtentzündlich.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36:Reizt die Augen.
S-Sätze Betriebsanweisung:
S16:Von Zündquellen fernhalten - Nicht rauchen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
It forms yellowish crystals with a sweet, very persistent, slightly animal musk odor.Musk ketone is prepared by Friedel–Crafts acetylation of 1,3-dimethyl-5-tert-butylbenzene and nitration of the resulting 2,6- dimethyl-4-tert-butylacetophenone with nitric acid.
Musk ketone is widely used as a fixative in blossom and fantasy compositions.
Chemische Eigenschaften
White to light yellow crystal powde
Occurrence
Has apparently not been reported to occur in nature.
Verwenden
Musk ketone is used as fragrance and fixative in after-shave lotions, perfumes, ete.
synthetische
Nitration of the corresponding benzene derivative (Bedoukian, 1967).
Definition
ChEBI: 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone is an aromatic ketone.
Allgemeine Beschreibung
Light yellow crystalline solid. Insoluble in water.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
Brandgefahr
Flash point data is not available for Musk ketone, however, Musk ketone is probably combustible.
Flammability and Explosibility
Not classified
läuterung methode
Purify the ketone by recrystallisation from MeOH. It has a strong odour of musk and is used in perfumery. [Fuson et al. J Org Chem 12 587 1947, Beilstein 7 IV 808.]

Musk ketone Upstream-Materialien And Downstream Produkte

4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

81-14-1, Musk ketone Verwandte Suche:

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