2-Amino-5-nitrophenol

Bezeichnung:2-Amino-5-nitrophenol

CAS-Nr121-88-0

Englisch Name:2-Amino-5-nitrophenol

CBNumberCB5436138

SummenformelC6H6N2O3

Molgewicht154.12

MOL-Datei121-88-0.mol

Synonyma

2-Amino-5-nitrophenol

2-Amino-5-nitrophenol physikalisch-chemischer Eigenschaften

Schmelzpunkt	198-202 °C (dec.) (lit.)
Siedepunkt	322.46°C (rough estimate)
Dichte	1.3617 (estimate)
Brechungsindex	1.6890 (rough estimate)
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Crystalline Powder
pka	8.08±0.19(Predicted)
Farbe	Rust brown to brown
Wasserlöslichkeit	insoluble
BRN	972974
CAS Datenbank	121-88-0(CAS DataBase Reference)
IARC	3 (Vol. 57) 1993
EPA chemische Informationen	2-Amino-5-nitrophenol (121-88-0)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-68-20/21/22
S-Sätze:	26-36/37-45-36/37/39-36
RIDADR	2811
WGK Germany	2
RTECS-Nr.	SJ6302500
TSCA	Yes
HS Code	29222900
Giftige Stoffe Daten	121-88-0(Hazardous Substances Data)
Toxizität	LD50 oral in rat: > 4gm/kg

Gefahreninformationscode (GHS)

2-Amino-5-nitrophenol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R68:Irreversibler Schaden möglich.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
Brown to rust Crystalline powder
Verwenden
Reactant for:• ;Diazotation and coupling reactions1• ;Preparation of biologically and pharmacologically active molecules2
Verwenden
2-Amino-5-nitrophenol has been used as starting material in the synthesis of series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides, as semi permanent (nonoxidative) hair colorant and as toner in permanent (oxidative) hair dye products, in synthesis of series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones, anticonvulsant agents. Also used as a reactant for, diazotation and coupling reactions, preparation of biologically and pharmacologically active molecules. It is also applied in hair dyes and to make azo dyes.
Verwenden
2-Amino-5-nitrophenol is used in hair dyes and as an intermediate in preparing azo dyes.
Definition
ChEBI: 2-Amino-5-nitrophenol is a member of 3-nitrophenols.
Allgemeine Beschreibung
Brown amorphous granules or powder. Melting point 198-202°C.
Air & Water Reaktionen
Is slowly oxidized by air at room temperature. Insoluble in water.
Reaktivität anzeigen
2-Amino-5-nitrophenol is a reducing agent. Incompatible with strong oxidizing agents. Reacts slowly with oxygen in the air at room temperature. Stable at temperatures up to 140°F for two weeks when kept in the dark and under nitrogen. Stable under nitrogen for up to 24 weeks 77°F. Incompatible with strong bases . Incompatible with acid chlorides and acid anhydrides.
Brandgefahr
Flash point data for 2-Amino-5-nitrophenol are not available. 2-Amino-5-nitrophenol is probably combustible.
Carcinogenicity
The potential carcinogenicity of 2-amino-5-nitrophenol was tested by NTP by oral administration (gavage) in corn oil to F344/N rats (100 and 200 mg/kg) and B6C3F1 mice (400 and 800 mg/kg) for 2 years. There was some evidence of carcinogenic activity in low-dose male rats, as indicated by increased incidence of acinar cell adenomas of the pancreas. No evidence of carcinogenic activity was found among female rats and the low-dose groups of male and female mice. The poor survival rates in the high-dose male rats and high-dose male and female mice reduced the sensitivity for detecting potential carcinogenic response.
läuterung methode
Crystallise the phenol from water. [Beilstein 13 IV 803.]

2-Amino-5-nitrophenol Upstream-Materialien And Downstream Produkte

2-Amino-5-nitrophenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

121-88-0, 2-Amino-5-nitrophenol Verwandte Suche:

Send Inquriy