4-Ethynylanisole

Bezeichnung:4-Ethynylanisole

Englisch Name:4-Ethynylanisole

CBNumberCB5403244

SummenformelC9H8O

Molgewicht132.16

4-Ethynylanisole physikalisch-chemischer Eigenschaften

Schmelzpunkt	28-29 °C (lit.)
Siedepunkt	87-91 °C/11 mmHg (lit.)
Dichte	1.019 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.563(lit.)
Flammpunkt	180 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Acetontrile (Slightly), Chloroform (Slightly)
Aggregatzustand	Liquid or Low Melting Solid
Farbe	Clear colorless to deep yellow or brown
Wasserlöslichkeit	Insoluble in water. Soluble in chloroform, acetone, dichloromethane, and methanol.
Sensitive	Light Sensitive
Stabilität	Light and Temperature Sensitive
InChIKey	KBIAVTUACPKPFJ-UHFFFAOYSA-N
CAS Datenbank	768-60-5(CAS DataBase Reference)
NIST chemische Informationen	4-CH3O-C6H4-CCH(768-60-5)

Sicherheit

Kennzeichnung gefährlicher	Xn,F
R-Sätze:	22
S-Sätze:	24/25
RIDADR	UN 1325 4.1/PG 2
WGK Germany	3
PackingGroup	II
HS Code	29093090

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Pale Yellow Oil
Verwenden
Intermediate in the synthesis of histamine H3-receptor antagonists. Also utilized to prepare its luminescent copper complex
Verwenden
4-Ethynylanisole was used in the synthesis of photo luminescent 1,2-dihydrophosphinines via a [4 + 2] cycloaddition. Along with an arylboronic acid and sodium azide in a copper-catalyzed, three-component synthesis of trisubstituted 1,2,4-triazoles. In a study of a gold (III)-catalyzed hydroamination of alkynes leading to N-vinylindoles3.
Verwenden
1,3-dipolar cycloaddition of acceptor-cyclopropylmethylsilanes affords functionalized cyclopentenes in good yields.1
Verwenden
Intermediates of Liquid Crystals
Definition
ChEBI: 1-Eth-1-ynyl-4-methoxybenzene is a member of methoxybenzenes.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 9, p. 230, 1998
Synthesis, p. 305, 1978
Tetrahedron, 62, p. 6673, 2006 DOI: 10.1016/j.tet.2005.12.077
Allgemeine Beschreibung
4-Ethynylanisole forms the corresponding propargyl aldehyde in good yield directly from DMF-dimethyl acetal without the need for making an acetylide salt. 1,3-dipolar cycloaddition of acceptor-cyclopropylmethylsilanes affords functionalized cyclopentenes in good yields.