FC 131

FC 131 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  C-X-C chemokine receptor 4 (CXCR4) is a receptor for the stromal cell-derived factor-1 (SDF-1) which is designated as chemokine ligand 12 (CXCL12). It is involved in cell progression, hematopoiesis, cancer, HIV entry, and rheumatoid arthritis. FC 131 is an inhibitor of CXCR4 activation by SDF-1 (IC₅₀ = 4.5 nM) and also blocks HIV-induced cytopathogenicity (EC₅₀ = 73 nM). FC 131 derivatives can be used for imaging CXCR4 and elucidating its function.

• Verwenden

  Cyclo[3-?(2-?naphthalenyl)?-?L-?alanylglycyl-?D-?tyrosyl-?L-?arginyl-?L-?arginyl] is a CXCR4 antagonist with anti-HIV properties.

• Definition

  ChEBI: Cyclo[3-(2-naphthalenyl)-l-alanylglycyl-d-tyrosyl-l-arginyl-l-arginyl] is an oligopeptide.

FC 131 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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