2-oxa-6-azaspiro[3.4]octane

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H227：Combustible liquid

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

  P405：Unter Verschluss aufbewahren.

2-oxa-6-azaspiro[3.4]octane Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.

• Application

  2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.

• Synthese

  Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.
  

2-oxa-6-azaspiro[3.4]octane Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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