4-Methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide

4-Methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  CGP 6140,CIBA-GEIGY Corp.

• Definition

  ChEBI: A thiourea resulting from the formal condensation of the secondary amino group of 1-methylpiperazine and the primary amino group of N-(4-nitrophenyl)benzene-1,4-diamine with carbonothioic O,O-acid.

• Manufacturing Process

  A solution of 4-nitro-4'-isothiocyanodiphenylamine in toluene was treated at 50°C with stirring with a solution N-methylpiperazine in toluene. After 3 hours the solution was filtered from the precipitate obtained. By recrystallization the crude product from methanol the 4-methyl-N-[4-[(4- nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide was obtained; melting point 191-196°C.

• Therapeutic Function

  Anthelmintic

4-Methyl-N-[4-[(4-nitrophenyl)amino]phenyl]-1-piperazinecarbothioamide Upstream-Materialien And Downstream Produkte