Gadoliniumtrichlorid

Bezeichnung:Gadoliniumtrichlorid

CAS-Nr10138-52-0

Englisch Name:GADOLINIUM CHLORIDE

CBNumberCB5227053

SummenformelCl3Gd

Molgewicht263.61

MOL-Datei10138-52-0.mol

Synonyma

Gadoliniumtrichlorid

Gadoliniumtrichlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt

609°C

Dichte

4,52 g/cm³

storage temp.

Hygroscopic, Room Temperature, under inert atmosphere

Löslichkeit

Water

Aggregatzustand

powder

Farbe

White to off-white

Wichte

4.52

Wasserlöslichkeit

Soluble in water.

Crystal Structure

UCl3 type

Sensitive

Hygroscopic

Merck

14,4326

crystal system

Six sides

Space group

P63/m

Lattice constant

a/nm	b/nm	c/nm	α/o	β/o	γ/o	V/nm3
0.737	0.737	0.411	90	90	120	0.1929

Stabilität

hygroscopic

CAS Datenbank

10138-52-0(CAS DataBase Reference)

EPA chemische Informationen

Gadolinium chloride (GdCl3) (10138-52-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	38
S-Sätze:	36/37
WGK Germany	3
RTECS-Nr.	ZC0230000
F	10-21
TSCA	Yes
HS Code	28273985

Gefahreninformationscode (GHS)

GADOLINIUM CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R38:Reizt die Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
Colorless crystals, soluble in water, purities up to 99.9%.
Verwenden
Gadolinium(III) Chloride is used as chelating agents, which is essential for biomedical applications. It is also employed in the synthesis and nuclear magnetic resonance (NMR) studies of paramagnetic GdPCTA-[12] and GdPCTA-[13] complexes. It plays an important role as contrast agent for magnetic resonance imaging and an macrophage inhibitor.
Verwenden
GadoliniuM chloride, anhydrous is a calcium-sensing receptor agonist and is known to work by inducing NLRP3 inflammasome activation in bone marrow-derived macrophages.
GdCl3 is used for preparing gadolinium metal.
Definition
ChEBI: Gadolinium trichloride is a gadolinium coordination entity. It has a role as a TRP channel blocker.
Biologische Aktivität
gadolinium chloride is a casr agonist. the casr can activate the nlrp3 inflammasome by increasing intracellular ca2+ and decreasing cellular cyclic amp. thus, casr agonists may serve as a useful tool for exploring nlrp3 inflammasome associated inflammatory diseases such as cryopyrin-associated periodic syndromes, gout and atherosclerosis. in addition, gadolinium chloride has been demonstrated to block trpml channel currents, as well as other transient receptor potential (trp) channels.1. lee gs, subramanian n, kim ai, et al. the calcium-sensing receptor regulates the nlrp3 inflammasome through ca2+ and camp. nature, 2012, 492(7427): 123-127.2. nagata k, zheng l, madathany t, et al. the varitint-waddler (va) deafness mutation in trpml3 generates constitutive, inward rectifying currents and causes cell degeneration. proceedings of the national academy of sciences of the united states of america, 2008, 105(1): 353-358.3. del favero g, florio c, codan b, et al. the stretch-activated channel blocker gd3+ reduces palytoxin toxicity in primary cultures of skeletal muscle cells. chemical research in toxicology, 2012, 25(9): 1912-1920.
Lager
Desiccate at RT

GADOLINIUM CHLORIDE Upstream-Materialien And Downstream Produkte

Gadoliniumtrichlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

10138-52-0, GADOLINIUM CHLORIDE Verwandte Suche:

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