Gadoliniumtrichlorid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

• Sicherheit

  P302+P352：BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

GADOLINIUM CHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R38:Reizt die Haut.

• S-Sätze Betriebsanweisung:

  S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

• Chemische Eigenschaften

  Colorless crystals, soluble in water, purities up to 99.9%.

• Verwenden

  Gadolinium(III) Chloride is used as chelating agents, which is essential for biomedical applications. It is also employed in the synthesis and nuclear magnetic resonance (NMR) studies of paramagnetic GdPCTA-[12] and GdPCTA-[13] complexes. It plays an important role as contrast agent for magnetic resonance imaging and an macrophage inhibitor.

• Verwenden

  GadoliniuM chloride, anhydrous is a calcium-sensing receptor agonist and is known to work by inducing NLRP3 inflammasome activation in bone marrow-derived macrophages.
  GdCl3 is used for preparing gadolinium metal.

• Definition

  ChEBI: Gadolinium trichloride is a gadolinium coordination entity. It has a role as a TRP channel blocker.

• Biologische Aktivität

  gadolinium chloride is a casr agonist. the casr can activate the nlrp3 inflammasome by increasing intracellular ca2+ and decreasing cellular cyclic amp. thus, casr agonists may serve as a useful tool for exploring nlrp3 inflammasome associated inflammatory diseases such as cryopyrin-associated periodic syndromes, gout and atherosclerosis. in addition, gadolinium chloride has been demonstrated to block trpml channel currents, as well as other transient receptor potential (trp) channels.1. lee gs, subramanian n, kim ai, et al. the calcium-sensing receptor regulates the nlrp3 inflammasome through ca2+ and camp. nature, 2012, 492(7427): 123-127.2. nagata k, zheng l, madathany t, et al. the varitint-waddler (va) deafness mutation in trpml3 generates constitutive, inward rectifying currents and causes cell degeneration. proceedings of the national academy of sciences of the united states of america, 2008, 105(1): 353-358.3. del favero g, florio c, codan b, et al. the stretch-activated channel blocker gd3+ reduces palytoxin toxicity in primary cultures of skeletal muscle cells. chemical research in toxicology, 2012, 25(9): 1912-1920.

• Lager

  Desiccate at RT

GADOLINIUM CHLORIDE Upstream-Materialien And Downstream Produkte

Gadoliniumtrichlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(177)Suppliers

10138-52-0, GADOLINIUM CHLORIDE Verwandte Suche: