5-Nitrothiazol-2-ylamin

Bezeichnung:5-Nitrothiazol-2-ylamin

CAS-Nr121-66-4

Englisch Name:2-Amino-5-nitrothiazole

CBNumberCB5143401

SummenformelC3H3N3O2S

Molgewicht145.14

MOL-Datei121-66-4.mol

Synonyma

5-Nitrothiazol-2-ylamin

5-Nitrothiazol-2-ylamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	195-200 °C (dec.) (lit.)
Siedepunkt	345.1±15.0 °C(Predicted)
Dichte	1.583 (estimate)
Brechungsindex	1.6740 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit	95% ethanol: soluble1g/150g at 20°C
Aggregatzustand	Powder
pka	1.26±0.10(Predicted)
Farbe	Yellow
Wasserlöslichkeit	<0.1 g/100 mL at 20 ºC
Sensitive	Light Sensitive
Merck	14,457
BRN	126797
Stabilität	Stable. Incompatible with strong acids, strong oxidizing agents, acid chlorides, acid anhydrides.
InChIKey	MIHADVKEHAFNPG-UHFFFAOYSA-N
CAS Datenbank	121-66-4(CAS DataBase Reference)
IARC	3 (Vol. 31, Sup 7) 1987
EPA chemische Informationen	2-Amino-5-nitrothiazole (121-66-4)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-36/37/38
S-Sätze:	26
WGK Germany	3
RTECS-Nr.	XJ2800000
F	8
Hazard Note	Irritant
TSCA	Yes
HS Code	29341000
Giftige Stoffe Daten	121-66-4(Hazardous Substances Data)

Gefahreninformationscode (GHS)

2-Amino-5-nitrothiazole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
greenish yellow, to orange or brown powder
Verwenden
2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein.
Definition
ChEBI: 2-Amino-5-nitrothiazole is a member of thiazoles and a C-nitro compound.
Vorbereitung Methode
Early production of 2-Amino-5-nitrothiazole was based on nitration of 2-acetylaminothiazole and careful hydrolysis. Direct nitration of 2-aminothiazole gives a cleaner product and is best achieved by adding 2-aminothiazole nitrate [57530-25-3] to concentrated sulfuric acid at 0 – 10 ℃. This process and the nitration of o-anisidine are the only large-scale processes based on rearrangement of an amine nitrate, and both are potentially hazardous due to the possibility of runaway exothermic reactions.
Allgemeine Beschreibung
Greenish-yellow to orange-yellow fluffy powder or a brown chunky powder. Slightly bitter taste. Used as a veterinary medicine.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
2-Amino-5-nitrothiazole may be sensitive to light. Incompatible with nitric acid and sulfuric acid. Also incompatible with strong oxidizing agents, strong acids, acid chlorides and acid anhydrides. A preparative hazard .
Brandgefahr
Flash point data for 2-Amino-5-nitrothiazole are not available. 2-Amino-5-nitrothiazole is probably combustible.
Sicherheitsprofil
Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental carcinogenic, tumorigenic, and neoplastigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SO,. Incompatible with HNO3 and H2SO4. An antiprotozoal agent.
mögliche Exposition
2-Amino-5-nitrothiazole is a synthetic veterinary antiprotozoal agent used since 1950 to treat farm fowl and pigeons. It is also used as an intermediate in manufacturing a group of dyes known as disperse azo dyes. It is not known to occur as a natural product. People may be exposed to 2-amino-5-nitrothiazole through contact with birds treated with the drug, releases from poultry farms, and occupational exposures in the dye industry.

2-Amino-5-nitrothiazole Upstream-Materialien And Downstream Produkte

5-Nitrothiazol-2-ylamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

121-66-4, 2-Amino-5-nitrothiazole Verwandte Suche:

Send Inquriy