ketomethylenebestatin

ketomethylenebestatin Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  Ketomethylenebestatin is a carba-analogue of the aminopeptidase (AP) inhibitor bestatin. This synthesis was carried out by a malonic ester alkylation with the suitably protected halomethyl ketone of (2S,3R)-AHPBA*), followed by a second alkylation with isobutyl bromide of the resulting 4-ketodiester, and subsequent decarboxylation and deprotection. Ketomethylenebestatin is 10 fold less effective as inhibitor of aminopeptidases than bestatin.

ketomethylenebestatin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(4)Suppliers