(3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate

(3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Octanoyl-L-carnitine may be used as an analytical standard in the following:
  
  • Separation and identification of underivatized octanoyl-L-carnitine in human plasma samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS).
  • Quantification of the analyte in biological samples of patients treated with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using high-performance liquid chromatography/tandem quadrupole mass spectrometry (HPLC-TQMS). The feasibility of adding L-carnitine to the peritoneal dialysis (PD) solution in APD-treated end-stage renal disease patients is investigated.
  
  It may be used as a test material for investigating its rate of oxidation by mitochondria, isolated from the livers of fed, starved and glucagon treated virgin and lactating rats.

• Definition

  ChEBI: The L-enantiomer of an O-octanoylcarnitine.

• Allgemeine Beschreibung

  Octanoyl-L-carnitine is a medium-chain endogenous ester of L-carnitine, obtained via acylcarnitine family transferase.

• Biochem/physiol Actions

  L-Octanoylcarnitine is the physiologically active form of octanoylcarnitine and is detected in medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. MCAD is characterized by intolerance to prolonged fasting, recurrent episodes of hypoglycemic coma with medium-chain dicarboxylic aciduria, impaired ketogenesis, and low plasma and tissue carnitine levels.

(3S)-3-octanoyloxy-4-trimethylazaniumylbutanoate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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