2-Hydroxyethylmethacrylat

Bezeichnung:2-Hydroxyethylmethacrylat

CAS-Nr868-77-9

Englisch Name:2-Hydroxyethyl methacrylate

CBNumberCB4690827

SummenformelC6H10O3

Molgewicht130.14

MOL-Datei868-77-9.mol

Synonyma

2-Hydroxyethylmethacrylat

Ethylenglycolmonomethacrylat

2-Methyl-2-propens?ure-2-hydroxyethylester

2-Hydroxyethylmethacrylat physikalisch-chemischer Eigenschaften

Schmelzpunkt	-12 °C
Siedepunkt	67 °C3.5 mm Hg(lit.)
Dichte	1.073 g/mL at 25 °C(lit.)
Dampfdichte	5 (vs air)
Dampfdruck	0.01 mm Hg ( 25 °C)
Brechungsindex	n20/D 1.453(lit.)
Flammpunkt	207 °F
storage temp.	2-8°C
Löslichkeit	Chloroform, Methanol (Slightly)
pka	13.83±0.10(Predicted)
Aggregatzustand	Liquid
Farbe	Clear
Geruch (Odor)	Ester like
Wasserlöslichkeit	soluble
FreezingPoint	-20
FreezingPoint	-96
Sensitive	Air Sensitive
BRN	1071583
Stabilität	Unstable - may polymerize in the absence of stabilizer. May be stabilized with, or contain small amounts of, diethylene glycol monomethacrylate, di(ethylene glycol)dimethacrylate, methacrylic acid. Incompatible with strong oxidizing agents, free radical initiators, peroxides, steel. Closed containers may explode if heated due to runaway polymer
InChIKey	WOBHKFSMXKNTIM-UHFFFAOYSA-N
LogP	0.42 at 25℃
CAS Datenbank	868-77-9(CAS DataBase Reference)
NIST chemische Informationen	2-Hydroxyethyl methacrylate(868-77-9)
EPA chemische Informationen	2-Hydroxyethyl methacrylate (868-77-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/38-43-36/37/38
S-Sätze:	26-36/37-28A-28
WGK Germany	1
RTECS-Nr.	OZ4725000
TSCA	Yes
HS Code	29161490
Giftige Stoffe Daten	868-77-9(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 5050 mg/kg LD50 dermal Rabbit > 3000 mg/kg

Gefahreninformationscode (GHS)

2-Hydroxyethyl methacrylate Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT
CHEMISCHE GEFAHREN
Der Stoff kann polymerisieren beim Erhitzen, bei Kontakt mit Peroxiden und unter Einfluss von Licht. Erhitzen kann zu sehr heftiger Verbrennung oder Explosion führen unter Bildung von beißendem Rauch. Der Stoff kann auch spontan polymerisieren, falls nicht stabilisiert.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt.
MAK: IIb (nicht festgelegt, aber Informationen vorhanden) Sensibilisierung der Haut (Sh); (DFG 2008).
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen, die Haut und die Atemwege. Verschlucken der Flüssigkeit kann zur Aufnahme in der Lunge führen; Gefahr der Aspirationspneumonie.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Kontakt kann zu Hautsensibilisierung führen. (Siehe ANMERKUNGEN.)
LECKAGE
Persönliche Schutzausrüstung: Chemikalienschutzanzug. Atemschutzfilter für organische Gase und Dämpfe. Ausgelaufene Flüssigkeit in abgedeckten Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen.
R-Sätze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
R43:Sensibilisierung durch Hautkontakt möglich.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S28:Bei Berührung mit der Haut sofort abwaschen mit viel . . . (vom Hersteller anzugeben).
Chemische Eigenschaften
colourless liquid
Verwenden
2-Hydroxyethyl methacrylate is used for preparation of hydrophilic polymers for biomedical devices.
Verwenden
2-Hydroxyethyl methacrylate is used in UV-curable inks and coatings. It is also used in adhesives, artificial nails, dental materials and lacquers. In dentistry, it is one of the main volatile acrylates along with methyl methacrylate. Further, it is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.
Verwenden
2-Hydroxyethyl methacrylate is the methacrylic monomer for use in UV inks, adhesives, lacquers, dental materials, artificial nails, etc.
Definition
2-Hydroxyethyl methacrylate is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Allgemeine Beschreibung
2-Hydroxyethyl methacrylate (HEMA) is biocompatible in nature. Polymeric hydrogel scaffold can be produced by polymerizing HEMA in water.
Hazard
30% grade (with xylene): Flammable, moderate fire risk.
Environmental Fate
2-Hydroxyethyl methacrylate's production and use in acrylic resins, enamels, and as a binder for non-woven fabrics may result in its release to the environment through various waste streams. If released into the air, a vapor pressure of 0.126 mm Hg at 25 °C indicates that 2-hydroxyethyl methacrylate will exist solely as a vapor in the ambient atmosphere. Vapor-phase 2-hydroxyethyl methacrylate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 16 hours. If released to soil, 2-hydroxyethyl methacrylate is expected to have very high mobility based upon an estimated Koc of 43. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 4.6X10-9 atm-cu m/mole. 2-Hydroxyethyl methacrylate is not expected to volatilize from dry soil surfaces based on its vapor pressure. If released into water, 2-hydroxyethyl methacrylate is not expected to adsorb to suspended solids and sediment in the water column based on the estimated Koc. 2-Hydroxyethyl methacrylate reached 92-100% of its theoretical BOD in 2 weeks using an activated sludge inoculum. Volatilization from water surfaces is not expected to be a necessary fate process based on this compound's estimated Henry's Law constant. An estimated BCF of 1.3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis of 2-hydroxyethyl methacrylate may be a significant process under basic conditions based upon a hydrolytic half-life of 4 hours at pH 11 for the structurally similar butyl acrylate; half-lives for butyl acrylate at pH 7, 8, and 9 were 4 years, 150 days, and 15 days, respectively. Occupational exposure to 2-hydroxyethyl methacrylate may occur through inhalation and dermal contact with this compound at workplaces where 2-hydroxyethyl methacrylate is produced or used. The general population may be exposed to 2-hydroxyethyl methacrylate via inhalation or dermal contact with acrylic resins or enamels containing this compound.
Stoffwechsel
2-hydroxyethyl methacrylate (HEMA) is a monomer based on methacrylic acid (MAA) used to produce biomaterials such as dental adhesive and composite resins. The process of polymerization, which is run in situ, is always incomplete, resulting in the presence of free monomers in the oral cavity. Moreover, monomers can be released from polymer-based tooth restorations through mechanical shearing and enzymatic degradation of polymers. They may penetrate the pulp through microchannels in the dentin structure. HEMA, like many of MAA-based monomers, is an ester, so it can be targeted by esterases when in organism and can undergo degradation. The main product of HEMA hydrolysis is MAA, which may undergo further degradation producing several intermediates of potential biological activity[1].
läuterung methode
Dissolve the ester in water and extract with n-heptane to remove ethylene glycol dimethacrylate (checked by gas-liquid chromatography and by NMR) and distil it twice under reduced pressure [Strop et al. J Phys Chem 80 694 1976]. [Beilstein 2 IV 1530.]

2-Hydroxyethyl methacrylate Upstream-Materialien And Downstream Produkte

2-Hydroxyethylmethacrylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

868-77-9, 2-Hydroxyethyl methacrylate Verwandte Suche:

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