Benzotriazol (in atembarer Form)

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H319：Verursacht schwere Augenreizung.

  H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P264：Nach Gebrauch gründlich waschen.

  P264：Nach Gebrauch gründlich waschen.

  P270：Bei Gebrauch nicht essen, trinken oder rauchen.

  P273：Freisetzung in die Umwelt vermeiden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

1H-Benzotriazole Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  WEISSES BIS BRAUNES KRISTALLINES PULVER.

• PHYSIKALISCHE GEFAHREN

  Staubexplosion der pulverisierten oder granulierten Substanz in Gemischen mit Luft möglich.

• CHEMISCHE GEFAHREN

  Zersetzung beim Erhitzen unter Bildung giftiger Rauche mit Aniline und Nitrobenzol. Schwache Säure in wässriger Lösung. Kann bei Vakuumdestillation explodieren.

• ARBEITSPLATZGRENZWERTE

  TLV nicht festgelegt.
  MAK: IIb (nicht festgelegt, aber Informationen vorhanden). (DFG 2008).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Inhalation des Aerosols und durch Verschlucken.

• INHALATIONSGEFAHREN

  Verdampfen bei 20°C vernachlässigbar; eine belästigende Partikelkonzentration in der Luft kann jedoch schnell erreicht werden.

• WIRKUNGEN BEI KURZZEITEXPOSITION

  WIRKUNGEN BEI KURZZEITEXPOSITION:
  Die Substanz reizt die Augen.

• WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION

  Wiederholter oder andauernder Kontakt kann zu Hautsensibilisierung führen.

• LECKAGE

  Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Atemschutzgerät, P1-Filter für inerte Partikel.

• R-Sätze Betriebsanweisung:

  R20/22:Gesundheitsschädlich beim Einatmen und Verschlucken.
  R36:Reizt die Augen.
  R52/53:Schädlich für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
  R5:Beim Erwärmen explosionsfähig.
  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
  R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
  R11:Leichtentzündlich.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
  S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
  S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
  S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

• Chemische Eigenschaften

  yellow to beige solid or Colorless needle-like crystals. Slightly soluble in cold water, ethanol and ether.

• Verwenden

  1H-Benzotriazole is an anticorrosive agent, which is useful in aircraft deicing and antifreeze fluids. It is also employed in dishwasher detergents. Further, it is used as a restrainer in photographic emulsions and also useful as a reagent for the determination of silver in analytical chemistry. It also serves as a corrosion inhibitor in the atmosphere and underwater. Further, it is utilized in the synthesis of amines from glyoxal.

• Definition

  ChEBI: 1H-Benzotriazole is the simplest member of the class of benzotriazoles that consists of a benzene nucleus fused to a 1H-1,2,3-triazole ring. It has a role as an environmental contaminant and a xenobiotic.

• synthetische

  1H-Benzotriazole is prepared by the reaction of o-phenylenediamine with nitrous acid in dilute sulfuric acid. Damschrodner and Peterson were able to synthesize the 1H-benzotriazole in a high yield (80%) by nitrosation of o-phenylenediamine with sodium nitrite in glacial acetic acid and water.
  
  Synthesis of 1H-benzotriazole via diazotization of o-phenylenediamine
  Reaction: Add o-phenylenediamine to 50°C water to dissolve, then add glacial acetic acid, cool down to 5°C, add sodium nitrite to stir the reaction. The reactant gradually turned dark green, the temperature rose to 70-80 ℃, the solution turned orange-red, placed at room temperature for 2 hours, cooled, filtered out the crystals, washed with ice water, dried to obtain the crude product, the crude product was distilled under reduced pressure, and collected 201 -204°C (2.0kPa) fraction, and then recrystallized with benzene to obtain 1H-Benzotriazole products with a melting point of 96-97°C, with a yield of about 80%.

• Application

  1H-Benzotriazole (BT) is a chemical used in a wide variety of industrial, commercial, and consumer products. It main used as an anticorrosive in metalworking, in art restoration, and as a tarnish remover and protective coating in the construction industry.
  In the aircraft industry, 1H-benzotriazole and tolyl benzotriazole are found to be the primary agents in most types of aircraft deicing/antiicing fluid (ADAFs).
  Benzotriazole is also used as a component of aircraft deicing fluid, pickling inhibitor in boiler scale removal, restrainer, developer and antifogging agent in photographic emulsions, corrosion inhibitor for copper, chemical intermediate for dyes, in pharmaceuticals, and as fungicide. (HSDB 1998).
  Benzotriazole(BTA), ethylenediamine tetraaceticacid(EDTA), and potassium iodide(KI) were used for preparing the polishing slurries.

• Synthesis Reference(s)

  The Journal of Organic Chemistry, 27, p. 185, 1962 DOI: 10.1021/jo01048a046

• Allgemeine Beschreibung

  White to light tan crystals or white powder. No odor.

• Air & Water Reaktionen

  Dust may form an explosive mixture in air. Slightly soluble in water.

• Reaktivität anzeigen

  The triazoles are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type substitution to the triazole ring. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives.

• Hazard

  Highly toxic by ingestion. May explode under vacuum distillation.

• Health Hazard

  ACUTE/CHRONIC HAZARDS: When heated to decomposition 1H-Benzotriazole emits toxic fumes. 1H-Benzotriazole can react violently during vacuum distillation.

• Brandgefahr

  Flash point data are not available for 1H-Benzotriazole. 1H-Benzotriazole is probably combustible.

• Flammability and Explosibility

  Non flammable

• Sicherheitsprofil

  Poison by intravenous route.Moderately toxic by ingestion and intraperitoneal routes.Questionable carcinogen with experimental tumorigenicdata. Mutation data reported. May detonate at 220°C or during vacuum distillation. When heated to decompositionit

• mögliche Exposition

  Because benzotriazoles are used in large quantities as a corrosion inhibitor, it is mainly through this type of use that benzotriazoles become an environmental contaminant. As a corrosion inhibitor and fire retardant, they are used in antifreeze in concentrations of 0.01-2.0% and in airplane deicing/antiicing fluids in unknown concentrations, up to 10% (Cancilla et al.,1997). Used antifreeze may leak or be poured down drains and thence enters the environment. Also, an estimated 80% of aircraft deicing/anti-icing fluids are deposited on the ground due to spray drift, jet blast, and wind shear during taxiing and takeoff, according to a recent study (Hartwell et al., 1995).

• Carcinogenicity

  Chronic (2-year) feeding studies were conducted. Rats were given 0, 6700, or 12,000 ppm in feed for 78 weeks and held for an additional 26 weeks. Mice were given 0, 11,700, or 23,500 ppm in feed in 104 weeks. The authors concluded that under the conditions shown in this study, there were no convincing evidence that 1-H-benzotriazole was carcinogenic in rats or mice.

• läuterung methode

  1,2,3-Benzotriazole crystallises from toluene, CHCl3, Me2NCHO or a saturated aqueous solution, and is dried at room temperature or in a vacuum oven at 65o. Losses are less if the material is distilled in a vacuum. CAUTION: may EXPLODE during distillation; necessary precautions must be taken. [Damschroder & Peterson Org Synth Coll Vol III 106 1955, Beilstein 26 III/IV 93.]

• Toxicity evaluation

  According to a 1977 EPA report, benzotriazole is considered to be of very low toxicity and a low health hazard to humans. In the same EPA report, two benzotriazole derivatives were reported to be mutagenic in bacterial systems. A year later, NIH published a report that there was no convincing evidence that the compound is carcinogenic (NIH, 1978). It is, however, more recently well established that 1-amino benzotriazole, with an amino group attached to one of the ring nitrogens, is a potent mechanism-based inhibitor of cytochrome P-450s via a benzyne intermediate (Ortiz de Montellano and Mathews, 1981), indicating that benzotriazoles as a class may interact with the P-450s. The P450s are important both for detoxifying a broad range of xenobiotics and for activating many compounds to carcinogens in mammalian systems.

1H-Benzotriazole Upstream-Materialien And Downstream Produkte

Benzotriazol (in atembarer Form) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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