2,4-Dichlorphenol

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H311：Giftig bei Hautkontakt.

  H314：Verursacht schwere Verätzungen der Haut und schwere Augenschäden.

  H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P260：Dampf/Aerosol/Nebel nicht einatmen.

  P273：Freisetzung in die Umwelt vermeiden.

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P301+P312：BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

  P303+P361+P353：BEI BERÜHRUNG MIT DER HAUT (oder dem Haar): Alle kontaminierten Kleidungsstücke sofort ausziehen. Haut mit Wasser abwaschen oder duschen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

2,4-Dichlorophenol Chemische Eigenschaften,Einsatz,Produktion Methoden

• ERSCHEINUNGSBILD

  FARBLOSE KRISTALLE MIT CHARAKTERISTISCHEM GERUCH.

• PHYSIKALISCHE GEFAHREN

  Die Dämpfe sind schwerer als Luft.

• CHEMISCHE GEFAHREN

  Beim Verbrennen Bildung ätzender Gase (Chlorwasserstoff). Beim Erhitzen bilden sich giftige Rauche. Reagiert sehr heftig mit starken Oxidationsmitteln.

• ARBEITSPLATZGRENZWERTE

  TLV nicht festgelegt (ACGIH 2005).
  MAK nicht festgelegt (DFG 2005).
  

• AUFNAHMEWEGE

  Aufnahme in den Körper durch Inhalation des Aerosols, über die Haut und durch Verschlucken.

• INHALATIONSGEFAHREN

  Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.

• WIRKUNGEN BEI KURZZEITEXPOSITION

  WIRKUNGEN BEI KURZZEITEXPOSITION:
  ätzend. Die Substanz verätzt die Augen, die Haut und die Atemwege. ätzend beim Verschlucken. Exposition in hohen Konzentrationen kann zum Tod führen. Exposition gegenüber kleinen Mengen der geschmolzenen oder flüssigen Form der Substanz kann zu erheblicher Hautresorption und schnellem Tod führen.

• LECKAGE

  Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Vollschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.

• R-Sätze Betriebsanweisung:

  R22:Gesundheitsschädlich beim Verschlucken.
  R24:Giftig bei Berührung mit der Haut.
  R34:Verursacht Verätzungen.
  R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
  R39/23/24/25:Giftig: ernste Gefahr irreversiblen Schadens durch Einatmen, Berührung mit der Haut und durch Verschlucken.
  R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
  R11:Leichtentzündlich.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
  S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
  S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
  S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
  S16:Von Zündquellen fernhalten - Nicht rauchen.

• Beschreibung

  2,4-DCP is a colorless crystalline solid with acharacteristic odor. Molecular weight=163.00; Boilingpoint=210℃; Freezing/Melting point=45.0℃; Flashpoint=113℃. Hazard Identification (based on NFPA-704M Rating System): Health 1, Flammability 1, Reactivity 0.Slightly soluble in water.

• Chemische Eigenschaften

  white to beige crystalline solid

• Chemische Eigenschaften

  2,4-DCP is a colorless crystalline solid with a characteristic odor

• Physikalische Eigenschaften

  Colorless to yellow crystals with a sweet, musty, or medicinal odor. At 40 °C, the average odor threshold concentration and the lowest concentration at which an odor was detected were 29 and 5.4 μg/L, respectively. Similarly, at 25 °C, the average taste threshold concentration and the lowest concentration at which a taste was detected were 2.5 and 0.98 μg/L, respectively (Young et al., 1996).

• Verwenden

  Intermediate in production of herbicidal chlorophenoxy acids such as 2,4- dichlorophenoxyacetic acid

• Verwenden

  2,4-Dichlorophenol is a chlorinated derivative of phenol and is used as an intermediate for the preparation of herbicide 2,4-dichlorophenoxyacetic acid (D435680).

• Definition

  ChEBI: A dichlorophenol that is phenol carrying chloro substituents at positions 2 and 4.

• Synthesis Reference(s)

  Synthetic Communications, 20, p. 2991, 1990 DOI: 10.1080/00397919008051517

• Allgemeine Beschreibung

  Colorless crystalline solid with a medicinal odor. Melting point 45°C. Sinks in water. Strong irritant to tissues; toxic by ingestion.

• Air & Water Reaktionen

  Insoluble in water.

• Reaktivität anzeigen

  2,4-Dichlorophenol can react vigorously with oxidizing agents. Can also react with acids or acid fumes. Incompatible with acid chlorides and acid anhydrides.

• Health Hazard

  Tremors, convulsions, shortness of breath, inhibition of respiratory system.

• Sicherheitsprofil

  Suspected carcinogen with experimental carcinogenic and teratogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Mutation data reported. Combustible when exposed to heat or flame. Can react vigorously with oxidizing materials. To fight fre, use alcohol foam, foam, CO2, dry chemical. When heated to decomposition, or on contact with acid or acid fumes, it emits hghly toxic fumes of Cl-. See also CHLOROPHENOLS.

• mögliche Exposition

  2,4-Dichlorophenol is a commercially produced substituted phenol used in the manufacture of industrial and agricultural products; in synthesis of pharmaceuticals. As an intermediate in the chemical industry, 2,4-DCP is utilized as the feedstock for the manufacture of 2,4-dichlorophenoxyacetic acid (2,4-D), and 2,4-D derivatives (germicides, soil sterilants, etc.); certain methyl compounds used in mothproofing, antiseptics and seed disinfectants. 2,4-DCP is also reacted with benzene sulfonyl chloride to produce miticides or further chlorinated to pentachlorophenol, a wood preservative. It is thus a widely used pesticide intermediate. The only group expected to be at risk for high exposure to 2,4-DCP is industrial workers involved in the manufacturing or handling of 2,4-DCP and 2,4-D

• Erste Hilfe

  If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, beginrescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

• Carcinogenicity

  In mammalian cells in vitro 2,4-DCP produced chromosomal aberrations and induced unscheduled DNA synthesis; it was negative for sister chromatid exchange in vivo and was mostly negative in bacterial assays.
  Oral exposure of pregnant rats to 750mg/kg/day for 10 gestational days induced slightly decreased fetal weight, delayed ossification of sternal and vertebral arches, and some early embryonic deaths.10 Maternal deaths also occurred at this dose, indicating that 2,4-DCP was not selectively toxic to embryos or fetuses. No effects were noted in dams or offspring exposed at 375mg/kg/day.
  A threshold limit value (TLV) has not been established for 2,4-dichlorophenol.

• Environmental Fate

  Biological. In activated sludge, 2.8% mineralized to carbon dioxide after 5 d (Freitag et al., 1985). In freshwater lake sediments, anaerobic reductive dechlorination produced 4-chlorophenol (Kohring et al., 1989). Chloroperoxidase, a fungal enzyme isolated from Caldariomyces fumago, converted 9 to 12% of 2,4-dichlorophenol to 2,4,6-trichlorophenol (Wannstedt et al., 1990). When 2,4-dichlorophenol was statically incubated in the dark at 25 °C with yeast extract and settled domestic wastewater inoculum, significant biodegradation with rapid adaptation was observed. At concentrations of 5 and 10 mg/L, 100 and 99% biodegradation, respectively, were observed after 7 d (Tabak et al., 1981). In activated sludge inoculum, 98.0% COD removal was achieved. The average rate of biodegradation was 10.5 mg COD/g?h (Pitter, 1976).
  Surface Water. Hoigné and Bader (1983) reported 2,4-dichlorophenol reacts with ozone at a rate constant of <1,500/M?sec at the pH range of 1.5 to 3.0.
  Groundwater. Nielsen et al. (1996) studied the degradation of 2,4-dichlorophenol in a shallow, glaciofluvial, unconfined sandy aquifer in Jutland, Denmark. As part of the in situ microcosm study, a cylinder that was open at the bottom and screened at the top was installed through a cased borehole approximately 5 m below grade. Five liters of water was aerated with atmospheric air to ensure aerobic conditions were maintained. Groundwater was analyzed weekly for approximately 3 months to determine 2,4-dichlorophenol concentrations with time. The experimentally determined first-order biodegradation rate constant and corresponding half-life were 0.20/d and 3.47 d, respectively.
  Photolytic. In distilled water, photolysis occurs at a slower rate than in estuarine waters containing humic substances. Photolysis products identified in distilled water were the three isomers of chlorocyclopentadienic acid. The following half-lives were reported for 2,4- dichlorophenol in estuarine water exposed to sunlight and microbes: 0.6 and 2.0 h during summer (24 °C) and winter (10 °C), respectively; in distilled water: 0.8 and 3.0 h during summer and winter, respectively; in poisoned estuarine water: 0.7 and 2.0 h during summer and winter, respectively (Hwang et al., 1986). When titanium dioxide suspended in an aqueous solution was irradiated with UV light (λ = 365 nm), 2,4-dichlorophenol was converted to carbon dioxide at a significant rate (Matthews, 1986). An aqueous solution containing hydrogen peroxide and irradiated by UV light (λ = 296 nm) converted 2,4-dichlorophenol to chlorohydroquinone and 1,4- dihydroquinone (Moza et al., 1988). A carbon dioxide yield of 50.4% was achieved when 2,4- dichlorophenol adsorbed on silica gel was irradiated with UV light (λ >290 nm) for 17 h (Freitag et al., 1985).
  Chemical/Physical. 2,4-Dichlorophenol will not hydrolyze to any reasonable extent (Kollig, 1993). Reported second-order rate constants for the reaction of 2,4-dichlorophenol and singlet oxygen in water at 292 K: 7 x 106/M?sec at pH 5.5, 2 x 106/M?sec at pH 6, 1.0 x 105/M?sec at pH 6.65, 1.5 x 106/M?sec at pH 7.0, 7.6 x 105/M?sec at pH 7.9, 1.20 x 104/M?sec at pH 9.0 to 9.6. At pH 8, the half-life of 2,4-dichlorophenol is 62 h (Scully and Hoigné, 1987). In an aqueous phosphate buffer at 27 °C, 2,4-dichlorophenol reacted with singlet oxygen at a rate of 5.1 x 106/M?sec (Tratnyek and Hoigné, 1991). At neutral pH, 2,4-dichlorophenol was completely oxidized by potassium permanganate (2.0 mg/L) after 15 min (quoted, Verschueren, 1983).

• Lager

  Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with 2,4-DCPyou should be trained on its proper handling and storage.Store in tightly closed containers in a refrigerator awayfrom oxidizers, acid, acid fumes, acid chlorides, acid anhydrides, caustics. A regulated, marked area should be established where this chemical is handled, used, or stored incompliance with OSHA Standard 1910.1045.

• Versand/Shipping

  UN2020 Chlorophenols, solid, Hazard Class: 6.1; Labels: 6.1-Poisonous materials

• läuterung methode

  Crystallise it from pet ether (b 30-40o). Purify it also by repeated zone melting, using a P2O5 guard tube to exclude moisture. It is very hygroscopic when dry. [Beilstein 6 IV 885.]

• Inkompatibilitäten

  Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with acids or acid fumes causes decomposition releasing poisonous chlorine gas. Incompatible with caustics, acid anhydrides; acid chlorides. Quickly corrodes aluminum; slowly corrodes zinc, tin, brass, bronze, copper and its alloys. May accumulate static electrical charges, and may cause ignition of its vapors.

• Waste disposal

  Dissolve in a combustible solvent and incinerate in a furnace equipped with afterburner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≧100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal

2,4-Dichlorophenol Upstream-Materialien And Downstream Produkte

2,4-Dichlorphenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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