2',4'-Dihydroxyacetophenon

Bezeichnung:2',4'-Dihydroxyacetophenon

CAS-Nr89-84-9

Englisch Name:2,4-Dihydroxyacetophenone

CBNumberCB4391766

SummenformelC8H8O3

Molgewicht152.15

MOL-Datei89-84-9.mol

Synonyma

2',4'-Dihydroxyacetophenon

2',4'-Dihydroxyacetophenon physikalisch-chemischer Eigenschaften

Schmelzpunkt	143-144.5 °C(lit.)
Siedepunkt	234.6°C (rough estimate)
Dichte	1.18 g/mL at 25 °C(lit.)
Brechungsindex	1.4945 (estimate)
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
pka	7.96±0.18(Predicted)
Aggregatzustand	Crystalline Powder or Crystals
Farbe	Off-white to pink to brown
PH	5 (1g/l, H2O, 20℃)
Sensitive	Moisture Sensitive
Merck	14,8140
BRN	1282505
InChIKey	SULYEHHGGXARJS-UHFFFAOYSA-N
LogP	1.480 (est)
CAS Datenbank	89-84-9(CAS DataBase Reference)
NIST chemische Informationen	Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9)
EPA chemische Informationen	Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-24/25
WGK Germany	2
RTECS-Nr.	AM7525000
Hazard Note	Irritant
TSCA	Yes
HS Code	29145000

Gefahreninformationscode (GHS)

2,4-Dihydroxyacetophenone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.
Verwenden
2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).
Definition
ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.
synthetische
Preparation by reaction of acetic acid on resorcinol,
with zinc chloride (Nencki reaction) (94%)
with boron trifluoride
with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%)
with polyphosphoric acid (63%)
with 70% perchloric acid (33%).
Synthesis Reference(s)
Journal of the American Chemical Society, 70, p. 428, 1948 DOI: 10.1021/ja01181a521
Sicherheitsprofil
Moderately toxic by ingestion. Experimental reproductive effects. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Synthese
2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.
target
Phospholipase (e.g. PLA)

2,4-Dihydroxyacetophenone Upstream-Materialien And Downstream Produkte

2',4'-Dihydroxyacetophenon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

89-84-9, 2,4-Dihydroxyacetophenone Verwandte Suche:

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