7-Amino-4-methylcumarin

Bezeichnung:7-Amino-4-methylcumarin

CAS-Nr26093-31-2

Englisch Name:Coumarin 120

CBNumberCB4354765

SummenformelC10H9NO2

Molgewicht175.18

MOL-Datei26093-31-2.mol

Synonyma

7-Amino-4-methylcumarin

7-Amino-4-methylcumarin physikalisch-chemischer Eigenschaften

Schmelzpunkt	223-226 °C (lit.)
Siedepunkt	306.47°C (rough estimate)
Dichte	1.1999 (rough estimate)
Brechungsindex	1.5060 (estimate)
storage temp.	2-8°C
Löslichkeit	Soluble in acetone (10 mg/ml) dimethyl sulfoxide (10 mg/ml) and dimethylformamide.
Aggregatzustand	Crystalline Powder
pka	1.89 ± 0.20, most basic, temperature: 25 °C
Farbe	Beige to brown
Sensitive	Light Sensitive
maximale Wellenlänge (λmax)	351 nm (MeOH); 342 nm (Buffer pH 7)
BRN	142231
Major Application	For authentification; dyelasers; color display devices; inks;monitoring underlying corrosion on coated aluminum;photoinitiating systems; recording materials;semiconductor devices; dye-sensitized solar cells(DSCs); mesoporous silica fibers; SiO2 sonogelhybrid materials; textiles; waveguides;whitening agents,
Biologische Anwendungen	Identifyingbacteria; measuring urinary kallikrein levels;monitoring platinum(iv) reduction and platinum(ii)reactions in cancer cells; as a substrate for measuringadipinylamidases activity, aromatic amino aciddecarboxylases activity, histone deacetylasesactivity, hydrolases/esterases activity,β-lactamases activity, microbial nitroreductasesactivity, penicillin G acylases activity,proteases/proteinases/peptidases activity,glutamyltransferases activity, tryptophanasesactivity; as an effective antitubercular agent; use astemperature sensor,
InChIKey	GLNDAGDHSLMOKX-UHFFFAOYSA-N
CAS Datenbank	26093-31-2(CAS DataBase Reference)
NIST chemische Informationen	Coumarin, 7-amino-4-methyl-(26093-31-2)
EPA chemische Informationen	2H-1-Benzopyran-2-one, 7-amino-4-methyl- (26093-31-2)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-20/21/22
S-Sätze:	26-36-37/39
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HS Code	32049000

Gefahreninformationscode (GHS)

Coumarin 120 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Coumarin 120 is Light yellow beige powder
Verwenden
Coumarin 120 is widely used fluorophore, well-known for preparing fluorogenic substrates for cystine aminopeptidase and other hydrolases. Used as reference compound in enzyme assays.
Verwenden
λ max 354 nm in EthanolSuitable as laser dye and used as a fluorescent labeling reagent for trace determination of enzymes.
Verwenden
suitable for determining polygalacturonase activity
Definition
ChEBI: Coumarin 120 is a member of 7-aminocoumarins. It has a role as a fluorochrome.
Allgemeine Beschreibung
7-Amino-4-methylcoumarin (coumarin120) is an aminocoumarin laser dye that can emit laser in the range of 370-760 nm. It has three intermolecular hydrogen bonded structures with C-H···O and N-H····O.
Biochem/physiol Actions
7-Amino-4-methylcoumarin is a coumarin derivative, which serves as a fluorescence reference standard to screen protease inhibitors.
Lager
+4°C
läuterung methode
Dissolve it in 5% HCl, filter and basify with 2M ammonia. The precipitate is dried in a vacuum and recrystallised from dilute EtOH. It yields a blue solution and is light sensitive. [Sigler Synthesis 614 1980, Kanaoka et al. Chem Pharm Bull Jpn 30 1485 1982, Beilstein 18/11 V 445.]

Coumarin 120 Upstream-Materialien And Downstream Produkte

7-Amino-4-methylcumarin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

26093-31-2, Coumarin 120 Verwandte Suche:

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