IWP-051

IWP-051 Chemische Eigenschaften,Einsatz,Produktion Methoden

• Beschreibung

  IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed >99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-051 achieves good alignment of potency, stability, selectivity, and pharmacodynamic effects while maintaining favorable pharmacokinetic properties with once-daily dosing potential in humans.

IWP-051 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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