Ethylmethansulfonat

Bezeichnung:Ethylmethansulfonat

CAS-Nr62-50-0

Englisch Name:Ethyl methanesulfonate

CBNumberCB4292779

SummenformelC3H8O3S

Molgewicht124.16

MOL-Datei62-50-0.mol

Synonyma

Ethylmethansulfonat

Ethylmethansulfonat physikalisch-chemischer Eigenschaften

Schmelzpunkt	<25 °C
Siedepunkt	85-86 °C/10 mmHg (lit.)
Dichte	1.206 g/mL at 20 °C
Dampfdruck	0.27 hPa (25 °C)
Brechungsindex	n20/D 1.418(lit.)
Flammpunkt	100 °C
storage temp.	2-8°C
Löslichkeit	50-100g/l
Aggregatzustand	liquid
Farbe	Colourless to Pale Yellow
Wasserlöslichkeit	Miscible with water.
Sensitive	Moisture Sensitive
Merck	14,3827
BRN	773969
Stabilität	Stable. Combustible. Incompatible with water, alkalies, oxidizing agents.
InChIKey	PLUBXMRUUVWRLT-UHFFFAOYSA-N
CAS Datenbank	62-50-0(CAS DataBase Reference)
IARC	2B (Vol. 7, Sup 7) 1987
NIST chemische Informationen	Methanesulfonic acid, ethyl ester(62-50-0)
EPA chemische Informationen	Ethyl methanesulfonate (62-50-0)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	46-22-40-36/37/38-45
S-Sätze:	53-23-36/37/39-45-36/37-37/39-26
RIDADR	2810
WGK Germany	3
RTECS-Nr.	PB2100000
F	10-21
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29041000
Giftige Stoffe Daten	62-50-0(Hazardous Substances Data)

Gefahreninformationscode (GHS)

Ethyl methanesulfonate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R46:Kann vererbbare Schäden verursachen.
R22:Gesundheitsschädlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Ethyl methane sulfonate is a clear liquid.
Chemische Eigenschaften
colourless liquid
Verwenden
Experimentally as mutagen, teratogen and brain carcinogen.
Verwenden
Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Definition
ChEBI: A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol.
Allgemeine Beschreibung
Clear colorless liquid. Denser than water.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
Ethyl methanesulfonate alkylates nucleophiles such as hydroxy, amino and sulfhydryl groups in model and biological materials. Is hydrolyzed by excess aqueous alkali to non-corrosive and non-toxic products. Is hydrolyzed by water to a highly corrosive product .
Brandgefahr
Ethyl methanesulfonate is combustible.
Biochem/physiol Actions
Ethyl methanesulfonate is a DNA ethylating agent, mutagenic to plants and animals and carcinogenic in mammals. It has been used as a model alkylating agent in studies of DNA repair processes. EMS induces base substitutions of guanine-cytosine (G/C) to adenine-thymine (A/T). EMS also generates point mutations and single nucleotide polymorphisms in genomes. EMS is potential chemical mutagen used for inducing mutation in rice, wheat and Arabidopsis thaliana.
Sicherheitsprofil
Confirmed carcinogen with experimental carcinogenic, neoplas tigenic, tumorigenic, and teratogenic data. Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES and ESTERS.
mögliche Exposition
Used as a research tool for mutagenesis and carcinogenesis studies. Was considered as a possible human male contraceptive. Also considered as a reversible male hemosterilant for insects and mammalian pests.
Carcinogenicity
Ethyl methanesulfonate is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Versand/Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.
Inkompatibilitäten
Vapors may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides. Contact with moisture may cause hydrolysis or other forms of decomposition

Ethyl methanesulfonate Upstream-Materialien And Downstream Produkte

Ethylmethansulfonat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

62-50-0, Ethyl methanesulfonate Verwandte Suche:

Send Inquriy