(αR,βS)-rel-Bedaquiline

(αR,βS)-rel-Bedaquiline Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

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• Verwenden

  (αR,βS)-rel-Bedaquiline is a promising diarylquinoline candidate in clinical development for the treatment of tuberculosis. (αR,βS)-rel-Bedaquiline inhibits mycobacterial ATP synthase and displays high activity against both drug-susceptible and multidrug-resistant strains of Mycobacterium tuberculosis.

• Definition

  ChEBI: Bedaquiline is a quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. It has a role as an antitubercular agent and an ATP synthase inhibitor. It is a member of quinolines, a member of naphthalenes, an organobromine compound, an aromatic ether, a tertiary alcohol and a tertiary amino compound. It is a conjugate base of a bedaquiline(2+).

(αR,βS)-rel-Bedaquiline Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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