3-IODO-2-TRIMETHYLSILYLMETHYL-1-PROPENE

3-IODO-2-TRIMETHYLSILYLMETHYL-1-PROPENE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Physikalische Eigenschaften

  bp 25 °C/0.5 mmHg.

• Verwenden

  3-Iodo-2-trimethylsilylmethyl-1-propene is widely used as a bifunctional conjunctive reagent that serves as a dipolar trimethylenemethane synthon; treatment with SnF2 affords a dianionic trimethylenemethane synthon.The most common use of this reagent is as a 1,3-dipolar synthon for trimethylenemethane (TMM).

• synthetische

  From the corresponding mesylate upon treatment with sodium iodide in acetone. The mesylate can be prepared from the commercially available alcohol.

• Lager

  3-Iodo-2-trimethylsilylmethyl-1-propene can be stored in the dark at -20 °C for up to 3 months without significant deterioration.

• Einzelnachweise

  1. Review of TMM and equivalents: Trost, B. M. AG(E) 1986, 25, 1.
  2. Trost, B. M.; Curran, D. P. TL 1981, 22, 5023.
  3. The alcohol can be prepared in two steps from 2-methyl-2-propen-1-ol: Trost, B. M.; Chan, D. M. T.; Nanninga, T. OS 1984, 62, 58.
  4. Trost, B. M.; Curran, D. P. JACS 1981, 103, 7380.
  5. Posner, G. H.; Asirvatham, E.; Hamill, T. G. JOC 1990, 55, 2132.

3-IODO-2-TRIMETHYLSILYLMETHYL-1-PROPENE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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