N,N,N',N'-Tetramethylnaphthalin-1,8-diamin

Bezeichnung:N,N,N',N'-Tetramethylnaphthalin-1,8-diamin

CAS-Nr20734-58-1

Englisch Name:1,8-Bis(dimethylamino)naphthalene

CBNumberCB4163778

SummenformelC14H18N2

Molgewicht214.31

MOL-Datei20734-58-1.mol

Synonyma

N,N,N',N'-Tetramethylnaphthalin-1,8-diamin

N,N,N',N'-Tetramethylnaphthalin-1,8-diamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	49-51 °C(lit.)
Siedepunkt	144-145°C (3.7505 mmHg)
Dichte	1.12
Flammpunkt	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Soluble in organic solvents.
Aggregatzustand	Crystalline Powder
pka	12.1(at 25℃)
Farbe	Pale brownish-pink
Wasserlöslichkeit	insoluble
Sensitive	Light Sensitive
Merck	14,3388
BRN	396782
InChIKey	GJFNRSDCSTVPCJ-UHFFFAOYSA-N
CAS Datenbank	20734-58-1(CAS DataBase Reference)
NIST chemische Informationen	1,8-Naphthalenediamine, N,N,N',N'-tetramethyl-(20734-58-1)

Sicherheit

Kennzeichnung gefährlicher	Xn,C
R-Sätze:	22-36/37/38-34
S-Sätze:	26-45-36/37/39
RIDADR	3259
WGK Germany	3
F	8-10-23
HazardClass	8
HS Code	29215900

Gefahreninformationscode (GHS)

1,8-Bis(dimethylamino)naphthalene Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
1,8-Bis(dimethylamino)naphtalene is pale brownish-pink crystalline powder
Verwenden
Very strong base in organic synthesis and catalysis.
Verwenden
1,8-Bis(dimethylamino)naphthalene, also referred to as protone sponge, is a lipophilic proton trapping agent. 1,8-Bis(dimethylamino)naphthalene is used in the matrix for mass spectroscopy analysis of lipids and fatty acids.
Verwenden
Very strong base with weak nucleophilic character due to steric effects.
Definition
ChEBI: N1,N1,N8,N8-tetramethylnaphthalene-1,8-diamine is a member of naphthalenes.
Allgemeine Beschreibung
Proton-sponge is also referred as 1,8-dimethylamino naphthalene. It is very strong base with weak nucleophilic character due to steric effects. It also participates in the reactions between arachno-6,9-C₂B₈H₁₄and selected acyl chlorides. It has been tested as an effective H⁺ scavenger.
Solubility in organics
Soluble in most organic solvents, such as methanol and chloroform.
läuterung methode
It is prepared by methylating 1,8-diaminonaphthalene, and likely impurities are methylated products. The tetramethyl compound is a stronger base than the unmethylated, di and trimethylated derivatives. The pKa values are: 1,8-(NH2)2 = 4.61, 1,8-(NHMe)2 = 5.61, 1-NHMe-8-NHMe2 = 6.43 and 1,8-(NMe2)2 = 12.34. The mixture is then treated with H2O at pH 8 (where all but the required base are protonated) and extracted with Et2O or CHCl3. The dried extract (K2CO3) yields the tetramethyldiamine on evaporation which can be distilled. It is a strong base with weak nucleophilic properties, e.g. it could not be alkylated by refluxing with EtI in MeCN for 4 days; and on treatment with methyl fluorosulfonate only the fluorosulfonate salt of the base is obtained. [NMR: Adler et al. J Chem Soc, Chem Commun 723 1968, Brown & Letang J Am Chem Soc 63 358 1941, Brzezinski et al. J Chem Soc Perkin Trans 2 857 1991.] Alternatively, crystallise proton sponge from EtOH and dry it in a vacuum oven. Store it in the dark in a CO2-free atmosphere. [Benoit et al. Can J Chem 65 996 1987, Beilstein 13 IV 344.]

1,8-Bis(dimethylamino)naphthalene Upstream-Materialien And Downstream Produkte

N,N,N',N'-Tetramethylnaphthalin-1,8-diamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

20734-58-1, 1,8-Bis(dimethylamino)naphthalene Verwandte Suche:

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