N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE Struktur

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE

Bezeichnung:N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE

Englisch Name:N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE

CBNumberCB4108669

SummenformelC8H18N2O2

Molgewicht174.24

N-N-BUTYL-N-BUTAN-4-OL-NITROSAMINE physikalisch-chemischer Eigenschaften

Siedepunkt	167 °C / 5mmHg
Dichte	1.01
Brechungsindex	1.4700-1.4740
Flammpunkt	147 °C
storage temp.	2-8°C
Aggregatzustand	clear liquid
pka	15.03±0.10(Predicted)
Farbe	Light yellow to Amber to Dark green
Stabilität	Stability
EPA chemische Informationen	4-(Butylnitrosoamino)butanol (3817-11-6)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	45-22
S-Sätze:	53
WGK Germany	3
RTECS-Nr.	EL1225000
HS Code	2929.90.5090

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
Chemische Eigenschaften
red liquid
Verwenden
N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.
Definition
ChEBI: A nitrosamine that has butyl and 4-hydroxybutyl substituents. In mice, it causes high-grade, invasive cancers in the urinary bladder, but not in any other tissues.
Allgemeine Beschreibung
Dark red liquid.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
A hydroxylated and nitrated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Biochem/physiol Actions
Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.