6BETA-HYDROXYTESTOSTERONE

Bezeichnung:6BETA-HYDROXYTESTOSTERONE

CAS-Nr62-99-7

Englisch Name:6BETA-HYDROXYTESTOSTERONE

CBNumberCB4108083

SummenformelC19H28O3

Molgewicht304.42

MOL-Datei62-99-7.mol

6BETA-HYDROXYTESTOSTERONE physikalisch-chemischer Eigenschaften

Schmelzpunkt	≥205 °C
Siedepunkt	479.8±45.0 °C(Predicted)
Dichte	1.19±0.1 g/cm3(Predicted)
Flammpunkt	9℃
storage temp.	2-8°C
Löslichkeit	Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
Aggregatzustand	A crystalline solid
pka	13.98±0.70(Predicted)
Farbe	white to off-white

Sicherheit

Kennzeichnung gefährlicher	Xn,T,F
R-Sätze:	61-40-39/23/24/25-23/24/25-11
S-Sätze:	53-22-36/37/39-45-36/37-16-7
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	3
HS Code	29372290

Gefahreninformationscode (GHS)

6BETA-HYDROXYTESTOSTERONE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R61:Kann das Kind im Mutterleib schädigen.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens. They mediate the metabolism of xenobiotics as well as certain endobiotics, including steroid hormones. CYP3A4 and CYP3A5 are cytochrome P450 enzymes whose expression is induced by glucocorticoids and certain xenobiotics, including many drugs and chemical carcinogens. They mediate the metabolism of xenobiotics as well as certain endobiotics, including steroid hormones. 6β-hydroxy Testosterone is a major metabolite produced from testosterone by the actions of CYP3A4 and CYP3A5, accounting for 75-80% of all metabolites formed from testosterone. The biological effects of 6β-hydroxy testosterone have been poorly studied.
Chemische Eigenschaften
White Solid
Verwenden
A metabolite of Testosterone. CONTROLLED SUBSTANC
Verwenden
A metabolite of Testosterone (T155000). CONTROLLED SUBSTANCE
Definition
ChEBI: A 17beta-hydroxy steroid that is testosterone bearing an additional hydroxy substituent at the 6beta-position.
Allgemeine Beschreibung
A Certified Spiking Solution^? suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical and diagnostic testing to endocrinology and sports testing. 6?-Hydroxytestosterone is a major urinary metabolite of testosterone, a hormone from the androgen group of steroids. Testosterone is an important sex hormone and anabolic steroid used as a performance-enhancing drug.

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