N-[2-[[5-[(Dimethylamino)methyl]furfuryl]thio]ethyl]-N'-methyl-2-nitrovinylidendiaminhydrochlorid

Bezeichnung:N-[2-[[5-[(Dimethylamino)methyl]furfuryl]thio]ethyl]-N'-methyl-2-nitrovinylidendiaminhydrochlorid

Englisch Name:Ranitidine Hydrochloride

CBNumberCB3685534

SummenformelC13H23ClN4O3S

Molgewicht350.86

Synonyma

N-[2-[[5-[(Dimethylamino)methyl]furfuryl]thio]ethyl]-N'-methyl-2-nitrovinylidendiaminhydrochlorid

N-[2-[[5-[(Dimethylamino)methyl]furfuryl]thio]ethyl]-N'-methyl-2-nitrovinylidendiaminhydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	134°C (dec.)
storage temp.	2-8°C
Löslichkeit	H₂O: 1.8 mg/mL
Aggregatzustand	solid
Farbe	tan
Wasserlöslichkeit	Soluble in water, 2-hydroxypropyl-beta-cyclodextrin, acetic acid, methanol, ethanol and dimethyl sulfoxide. Insoluble in chloroform.
Sensitive	Hygroscopic
Merck	14,8110
BCS Class	3/1
Stabilität	Hygroscopic
CAS Datenbank	66357-59-3(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	F,T
R-Sätze:	20/21/22-39/23/24/25-23/24/25-11
S-Sätze:	22-24/25-45-36/37-16-7
WGK Germany	2
RTECS-Nr.	KM6557000
HS Code	2932190002

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Off-White Crystalline Solid
Verwenden
An H-2 histamine receptor antagonistRanitidine hydrochloride is mainly used as an H2-receptor antagonist and helps in the treatment of gastrointestinal lesions because of excessive gastric acid secretion. It also serves as an antiulcer drug.
Verwenden
antifungal
Verwenden
A histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.
Trademarks
Zantac (GlaxoSmithKline).
Biologische Aktivität
ranitidine is a histamine h2-receptor antagonist that inhibits stomach acid production.ranitidine (zantac) is a histamine h2-receptor antagonist with ic50 of 3.3 ± 1.4 um. it inhibits stomach acid production. it is also used alongside fexofenadine and oth
Kontakt-Allergie
Ranitidine, an H2-receptor antagonist, can cause contact dermatitis within the pharmaceutical industry and in health care workers, or may induce systemic drug reactions in patients.
Biochem/physiol Actions
H2 histamine receptor antagonist; anti-ulcer agent.
Lager
+4°C (desiccate)