4-Nitrophthalimid

Bezeichnung:4-Nitrophthalimid

CAS-Nr89-40-7

Englisch Name:4-Nitrophthalimide

CBNumberCB3681521

SummenformelC8H4N2O4

Molgewicht192.13

MOL-Datei89-40-7.mol

Synonyma

4-Nitrophthalimid

4-Nitrophthalimid physikalisch-chemischer Eigenschaften

Schmelzpunkt	206 °C
Siedepunkt	328.09°C (rough estimate)
Dichte	1.5513 (rough estimate)
Brechungsindex	1.4900 (estimate)
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	powder to crystal
pka	7.79±0.20(Predicted)
Farbe	Yellow powder
Wasserlöslichkeit	<0.01 g/100 mL at 18 ºC
BRN	180224
Stabilität	Stable. Combustible. Incompatible with moisture, water, strong oxidising agents, strong bases.
InChIKey	ANYWGXDASKQYAD-UHFFFAOYSA-N
CAS Datenbank	89-40-7(CAS DataBase Reference)
NIST chemische Informationen	4-Nitro-phthalimide(89-40-7)
EPA chemische Informationen	4-Nitrophthalimide (89-40-7)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	37/39-26-36-24/25
WGK Germany	3
RTECS-Nr.	TI5625000
Hazard Note	Irritant
TSCA	Yes
HS Code	29251900
Toxizität	mmo-sat 333 mg/plate EMMUEG 11(Suppl 12),1,88

Gefahreninformationscode (GHS)

4-Nitrophthalimide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
slight yellow powder
Verwenden
4-Nitrophthalimide is used as intermediate of organic synthesis and fluorescent dyes, it can be used to produce azo dyes, luminol, etc. It can also be used to prepare 4-nitrophthalonitrile, 5-cyanophthalide and other drug intermediates.
synthetische
4-Nitrophthalimide is synthesized from phthalimide by nitration. Cool the fuming nitric acid to below 5°C, slowly add concentrated sulfuric acid dropwise, and control the temperature to 10-13°C. Plus phthalimide. Leave at room temperature overnight. Then, it was poured into ice water with stirring, and the precipitate was precipitated below 20°C. Filter, wash with water, dry, and then recrystallize from ethanol to obtain 4-nitrophthalimide with a yield of 60%.
Allgemeine Beschreibung
Yellow powder.
Air & Water Reaktionen
4-Nitrophthalimide can be hydrolyzed. . Insoluble in water.
Reaktivität anzeigen
A nitrated amine. Amines are combustible. The combustion of amines yields noxious NOx. REACTIVITY - Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.
Brandgefahr
Flash point data for 4-Nitrophthalimide are not available, however 4-Nitrophthalimide is probably combustible.
Sicherheitsprofil
Mutation data reported. Whenheated to decomposition it emits toxic vapors of NOx.
Synthese
200 mL of sulfuric acid and 50 mL of fuming nitric acid were cooled on an ice bath and 40 g (0.272 mol) phthalimide was added in portions within 1-1.5 hours so as not to exceed the internal temperature beyond 10-15 ??C. The mixture was stirred over ice bath for half an hour and the internal temperature was raised to 35 ??C, and yellow particles were observed to dissolve. The mixture was stirred for an additional 1 hour, then cooled to 0 ??C again and poured onto 1 kg of ice water mixture. Yellow 4-nitrophthalonitrile precipitated, it was filtered and washed with water until the filtrate was neutral to blue litmus paper. It was crystallized from 850-900 mL of ethyl alcohol. Bright yellow crystals were filtered, washed with cold ethyl alcohol, and dried in a vacuum oven at 80-90 ??C.

4-Nitrophthalimide Upstream-Materialien And Downstream Produkte

4-Nitrophthalimid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

89-40-7, 4-Nitrophthalimide Verwandte Suche:

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