1,4-Dioxaspiro[4.5]decan-8-one

Bezeichnung:1,4-Dioxaspiro[4.5]decan-8-one

CAS-Nr4746-97-8

Englisch Name:1,4-Dioxaspiro[4.5]decan-8-one

CBNumberCB3496677

SummenformelC8H12O3

Molgewicht156.18

MOL-Datei4746-97-8.mol

1,4-Dioxaspiro[4.5]decan-8-one physikalisch-chemischer Eigenschaften

Schmelzpunkt	70-73 °C (lit.)
Siedepunkt	112C
Dichte	1.0887 (rough estimate)
Brechungsindex	1.4430 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Soluble in chloroform & methanol.
Aggregatzustand	Crystalline Powder or Crystals
Farbe	White to beige
Sensitive	Moisture Sensitive
BRN	117631
InChI	InChI=1S/C8H12O3/c9-7-1-3-8(4-2-7)10-5-6-11-8/h1-6H2
InChIKey	VKRKCBWIVLSRBJ-UHFFFAOYSA-N
SMILES	O1C2(CCC(=O)CC2)OCC1
CAS Datenbank	4746-97-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	22-24/25-36/37/39-26
WGK Germany	3
F	8-10-21
Hazard Note	Irritant
HS Code	29110000

Gefahreninformationscode (GHS)

1,4-Dioxaspiro[4.5]decan-8-one Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
1,4-Dioxaspiro[4.5]decan-8-one is white to beige crystalline powder or crystals
Verwenden
1,4-Dioxaspiro[4.5]decan-8-one is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.
Verwenden
Intermediates of Liquid Crystals
Verwenden
1,4-Cyclohexanedione is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.
Application
1,4-Dioxaspiro[4.5]decan-8-one can be used:
(1) Used in a study of microwave-assisted reductive amination.
(2) Via a novel aromatization process, this bicyclic frame can be converted into a series of 5-alkoxytryptamine derivatives including serotonin, melatonin and bufotenin.
läuterung methode
Recrystallise it from pet ether. It sublimes slowly on attempted distillation. Also purify it by dissolving it in Et2O and adding pet ether (b 60-80o) until turbid and cooling. [Gardner et al. J Am Chem Soc 22 1206 1957, Britten & Lockwood J Chem Soc Perkin Trans 1 1824 1974.] [Beilstein 19/4 V 93.]

1,4-Dioxaspiro[4.5]decan-8-one Upstream-Materialien And Downstream Produkte

1,4-Dioxaspiro[4.5]decan-8-one Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

4746-97-8, 1,4-Dioxaspiro[4.5]decan-8-one Verwandte Suche:

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