γ-Secretase Inhibitor I - Calbiochem

γ-Secretase Inhibitor I - Calbiochem Chemische Eigenschaften,Einsatz,Produktion Methoden

• Allgemeine Beschreibung

  A potent, cell-permeable, reversible γ-secretase inhibitor that preferentially appears to inhibit the secretion of Aβ_1-40 (>90%) over Aβ_1-42 (~15%). Aβ_total IC₅₀ ~ 15 M; Aβ_1-40 IC₅₀ ~ 22 M; Aβ_1-42 IC₅₀ >50 M in CHO cells stable transfected with the cDNA encoding βAPP695.

• Biochem/physiol Actions

  Primary Targetsecretion of Aβ

γ-Secretase Inhibitor I - Calbiochem Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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