Polysorbate 20

Bezeichnung:Polysorbate 20

CAS-Nr9005-64-5

Englisch Name:Polysorbate 20

CBNumberCB3462544

SummenformelC26H50O10

Molgewicht522.6692

MOL-Datei9005-64-5.mol

Polysorbate 20 physikalisch-chemischer Eigenschaften

Schmelzpunkt	98.9 °C (decomp)
Siedepunkt	100 °C
Dichte	1.11 g/mL at 20 °C
Dampfdruck	<1.4 hPa (20 °C)
Brechungsindex	n20/D 1.468(lit.)
FEMA	2915 \| POLYSORBATE 20
Flammpunkt	>230 °F
storage temp.	Store below +30°C.
Löslichkeit	100 g/L
Aggregatzustand	viscous liquid
Farbe	Amber
Wichte	1.090～1.130 (20/20℃)
Säure-Base-Indikators(pH-Indikatoren)	7
PH	6-8 (50g/l, H2O, 20℃)
Geruch (Odor)	mild alcohol odor
Geruchsart	alcoholic
Wasserlöslichkeit	100 g/L
hydrophiles-lipophiles Gleichgewicht (HLB)	16.7
Stabilität	Stable. Incompatible with strong oxidizing agents.
EPA chemische Informationen	Polysorbate 20 (9005-64-5)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	22-36/37/38-37/38-41
S-Sätze:	24/25-36/37/39-36-26
WGK Germany	1
RTECS-Nr.	TR7400000
F	10-23
TSCA	Yes
HS Code	34021300
Giftige Stoffe Daten	9005-64-5(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 38900 mg/kg

Gefahreninformationscode (GHS)

Polysorbate 20 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Yellow liquid
Chemische Eigenschaften
Polysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a warm, somewhat bitter taste.
Verwenden
polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.
Verwenden
Used for solubilizing membrane proteins during isolation and purification.Polysorbate 20 is used as a wetting agent in flavored mouth drops. It acts as a washing agent in Western blots and ELISAs and prevents antibody binding. It is a solubilizing agent of membrane proteins. In pharmaceutical chemistry, it is used as an excipient to stabilize emulsions and suspensions. Further, it is used as a dispersing agent, stabilizer, lubricator and also used in creams, salves, ointments, protective creams, balms, pomades, lipsticks, mascaras and glosses.
synthetische
polysorbate 20 is prepared by condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups.
Definition
ChEBI: Polysorbate 20 (Tween 20) is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. It is a surfactant and emulsifier used in cleaners and personal care products.
Trademarks
Tween 20 (ICI Americas).
Allgemeine Beschreibung
Polysorbate 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.
Auswirkungen auf die Gesundheit
Polysorbate 20 was a skin irritant in dermatitis patients but was reported not to induce irritant responses when applied to the intact skin of health volunteers. It produced, at worst, minimal irritation in the eyes of rabbits. Only a small number of cases of skin sensitization have been reported in humans, although a moderate to strong sensitizing potential was seen in guinea-pigs treated by intradermal injection.
Flammability and Explosibility
Non flammable
Sicherheitsprofil
Moderately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Polysorbate 20 Upstream-Materialien And Downstream Produkte

Polysorbate 20 Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

9005-64-5, Polysorbate 20 Verwandte Suche:

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