OXYTHIAMINE HYDROCHLORIDE

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H302：Gesundheitsschädlich bei Verschlucken.

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P261：Einatmen von Staub vermeiden.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

OXYTHIAMINE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  thiamine antagonist

• Verwenden

  Oxythiamine chloride hydrochloride is suitable for use:
  
  • as a reference standard for calibration curve generation in liquid chromatography-tandem mass spectrometry (LC-MS/MS) for oxythiamine pyrophosphate (OTPP) quantification in red blood cells
  • as a thiamine transport inhibitor in human mammary epithelial cells (HMEC) and breast cancer cell lines
  • in the synthesis of oxythiamineH picrolonate salt
  
  

• Definition

  ChEBI: A hydrochloride obtained by combining oxythiamine chloride with one molar equivalent of hydrochloric acid.

• Allgemeine Beschreibung

  Oxythiamine is a thiamine antimetabolite and the source through diet is by consuming acidic thiamine rich foods.

• Biochem/physiol Actions

  Oxythiamine (OT) is a thiamine antagonist. It is a transketolase inhibitor and is employed to study anti-metastatic mechanisms, especially those involving metalloproteinases (MMP). It significantly sensitizes human hepatocellular carcinoma cells (HCC) to sorafenib, favoring tumor suppression.

OXYTHIAMINE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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