Isoprenalinsulfat

Isoprenaline sulphate Chemische Eigenschaften,Einsatz,Produktion Methoden

• Originator

  Isonorin,Smith, Miller and Patch,US,1949

• Verwenden

  Bronchodilator.

• Manufacturing Process

  As described in US Patent 2,308,232, 100 g 3,4-dihydroxy-ω- chloroacetophenone, 200 cc ethyl alcohol and 200 cc of about 50% aqueous isopropylamine solution are boiled during 3 hours on the water bath with the use of a reflux condenser, whereupon neutralizing with diluted sulfuric acid is carried out and the sulfate, obtained upon cooling, from alcohol of 50% is recrystallized; its MP is 245°C.
  21 g 3,4-dihydroxy-ω-isopropylaminoacetophenone sulfate are hydrogenated with 50 cc methyl alcohol and 50 cc water, 0.5 g carbon and 3 cc palladium chloride solution of 2%. After 2 hours the hydrogen absorption comes to a standstill, after the theoretical quantity of hydrogen has been absorbed. After concentrating, the isopropylaminomethyl-(3,4-dihydroxyphenyl)carbinolsulfate crystallizes out. It has a MP of 180°C after refining.

• Trademarks

  Medihaler-ISO (3M Pharmaceuticals).

• Therapeutic Function

  Bronchodilator

Isoprenaline sulphate Upstream-Materialien And Downstream Produkte

Isoprenalinsulfat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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