Pimelinsure

Bezeichnung:Pimelinsure

Englisch Name:Pimelic acid

CBNumberCB3329360

SummenformelC7H12O4

Molgewicht160.17

Synonyma

Pimelinsure

Pimelinsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	103-105 °C(lit.)
Siedepunkt	212 °C10 mm Hg(lit.)
Dichte	1,329 g/cm³
Brechungsindex	1.4352 (estimate)
Flammpunkt	212°C/10mm
storage temp.	Store below +30°C.
Löslichkeit	ethanol: 0.1 g/mL, clear to very faintly hazy
Aggregatzustand	Powder
pka	4.71(at 25℃)
Farbe	White to slightly beige
PH	3.77(1 mM solution);3.25(10 mM solution);2.74(100 mM solution)
Wasserlöslichkeit	25 g/L (13 ºC)
Merck	14,7431
BRN	1210024
Stabilität	Stable. Incompatible with oxidizing agents, bases. Combustible.
InChIKey	WLJVNTCWHIRURA-UHFFFAOYSA-N
LogP	0.610
CAS Datenbank	111-16-0(CAS DataBase Reference)
NIST chemische Informationen	Heptanedioic acid(111-16-0)
EPA chemische Informationen	Heptanedioic acid (111-16-0)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	2
RTECS-Nr.	TK3677000
Hazard Note	Irritant
TSCA	Yes
HS Code	29171990
Toxizität	LD50 orally in Rabbit: 7000 mg/kg

Gefahreninformationscode (GHS)

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Pimelic acid is the organic compound with the formula HO₂C(CH₂)₅CO₂H which has been synthesized from cyclohexanone and from salicylic acid. In the former route, the additional carbon is supplied by dimethyloxalate, which reacts with the enolate.
This acid (heptanedioic acid), from the Greek pimelh (pimele fat), as adipic acid, was isolated from oxidized fats. It was obtained in 1884 by Ganttner F et al. as a product of ricinoleic acid (hydroxylated oleic acid) from castor oil.
Chemische Eigenschaften
white solid
Verwenden
The major uses of pimelic acid are in plasticizers and polymers.
Verwenden
Pimelic Acid is a metabolite found in four biofluids from dairy cows that may be used as biomarkers of milk.
Definition
ChEBI: An alpha,omega-dicarboxylic acid that is pentane with two carboxylic acid groups at positions C-1 and C-5.
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 3425, 1956 DOI: 10.1021/ja01595a044
Organic Syntheses, Coll. Vol. 2, p. 531, 1943
Synthesis, p. 54, 1988
läuterung methode
Crystallise the acid from water or from *benzene containing 5% diethyl ether. [Beilstein 1 IV 2003.]