Xanthen-9-on

Bezeichnung:Xanthen-9-on

CAS-Nr90-47-1

Englisch Name:Xanthone

CBNumberCB3304187

SummenformelC13H8O2

Molgewicht196.2

MOL-Datei90-47-1.mol

Synonyma

Xanthen-9-on

Xanthen-9-on physikalisch-chemischer Eigenschaften

Schmelzpunkt	172-174 °C(lit.)
Siedepunkt	349-350 °C730 mm Hg(lit.)
Dichte	1.1607 (rough estimate)
Brechungsindex	1.6000 (estimate)
Flammpunkt	350-351°C
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Methanol (Slightly, Heated)
Aggregatzustand	Solid
Farbe	White to Light Purple
Wasserlöslichkeit	It is Soluble in water (partly), chloroform, hot Toluene, ether (slightly), and hot alcohol.
Merck	14,10062
BRN	140443
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChIKey	JNELGWHKGNBSMD-UHFFFAOYSA-N
CAS Datenbank	90-47-1(CAS DataBase Reference)
NIST chemische Informationen	Xanthone(90-47-1)
EPA chemische Informationen	9H-Xanthen-9-one (90-47-1)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22
S-Sätze:	24/25-62-45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS-Nr.	ZD5711000
Hazard Note	Irritant
TSCA	Yes
HS Code	29329990

Gefahreninformationscode (GHS)

Xanthone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
Xanthone is a compound that has been shown to have a significant cytotoxicity against HL-60 cells and to inhibit the cyclase enzyme. It also inhibits the protein production of mcl-1, which is necessary for the development of cancer cells.
Chemische Eigenschaften
off-white powder
Verwenden
Xanthone is used predominantly as oxygenated polycyclic aromatic compounds, and as a vasorelaxant. It can be used as a fluorescent agent, as well as an intermediate in organic synthesis and chemical research.
Verwenden
Acts as an inhibitor of human cancer cell lines.
Definition
A colorless crystalline organic compound found as a pigment in gentians and other flowers. It is used as an insecticide and in making dyestuffs.
Application
Xanthone has antiinflammatory activity and can be used in treating infectious diseases such as tuberculosis, malaria, and leprosy. The biological properties of it are shown by its ability to scavenge anion radicals and to act as a fluorescence probe for coumarin derivatives.
Definition
ChEBI: The parent compound of the xanthone class consisting of xanthene bearing a single oxo substituent at position 9.
Synthesis Reference(s)
The Journal of Organic Chemistry, 37, p. 4204, 1972 DOI: 10.1021/jo00798a059
läuterung methode
It has also been recrystallised from n-hexane three times and sublimed in vacuo. [Saltiel J Am Chem Soc 108 2674 1986]. [Beilstein 17 H 354, 17 I 190, 17 II 378, 17 III/IV 5292, 17/10 V 430.]

Xanthone Upstream-Materialien And Downstream Produkte

Xanthen-9-on Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

90-47-1, Xanthone Verwandte Suche:

Send Inquriy