1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

Bezeichnung:1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

CAS-Nr6974-32-9

Englisch Name:beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate

CBNumberCB3292813

SummenformelC28H24O9

Molgewicht504.48

MOL-Datei6974-32-9.mol

Synonyma

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose physikalisch-chemischer Eigenschaften

Schmelzpunkt	128-130 °C
Siedepunkt	621.0±55.0 °C(Predicted)
alpha	24.4 º (c=1, pyridine)
Dichte	1.35±0.1 g/cm3(Predicted)
Brechungsindex	24 ° (C=1, Pyridine)
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated),
Aggregatzustand	Liquid
Farbe	Clear slightly yellow or greenish to brown
Optische Aktivität	[α]20/D +24.3°, c = 1 in pyridine
BRN	100243
InChIKey	GCZABPLTDYVJMP-CBUXHAPBSA-N
SMILES	C(OC)(=O)C1=CC=CC=C1[C@@H]1[C@@H](OC(=O)C2=CC=CC=C2)[C@@H](OC(=O)C2=CC=CC=C2)[C@H](OC(C)=O)O1 \|&1:10,11,21,31,r\|
CAS Datenbank	6974-32-9(CAS DataBase Reference)
EPA chemische Informationen	.beta.-D-Ribofuranose, 1-acetate 2,3,5-tribenzoate (6974-32-9)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/38
S-Sätze:	22-24/25-37/39-26
WGK Germany	3
TSCA	Yes
HS Code	29400090

Gefahreninformationscode (GHS)

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
An inhibitor of neutrophil-keyhole limpet hemocyanin adhesion
Application
Beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate, also known as 1-O-Acetyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranose, is a ribose-derived compound used in nucleoside synthesis.
Synthese
Rac-(2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-hydroxytetrahydrofuran-3,4-diyl dibenzoate was dissolved in dry pyridine, and the solution was slowly added dropwise with acetic anhydride in an ice water bath, then stirred for 30 minutes. Then, the ice water bath was removed, and the solution was stirred at room temperature for 7 hours and then heated to 40°C. This temperature was kept for an hour. The solution was added with broken ice and then stirred until the broken ice melted. The reaction solution was poured into ice water and extracted with chloroform. The organic layer was washed sequentially with ice water, pre-cooled sulfuric acid, and saturated sodium bicarbonate until the water layer showed weak alkaline, then washed with ice water until the water layer showed neutral, dried over anhydrous sodium sulfate for more than 4 hours, and then drawn off under reduced pressure, to obtain the light yellow syrup-like beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate (92.1%).
läuterung methode
Recrystallise it from EtOH or isoPrOH. [Helv Chim Acta 42 1171 1959, NMR: J Org Chem 33 1799 1968, IR: Chem Pharm Bull Jpn 11 188 1963, Beilstein 17/6 V 213.]

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Upstream-Materialien And Downstream Produkte

1-O-Acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6974-32-9, beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Verwandte Suche:

Send Inquriy